12 Result(s)

Article

Circulating microRNA’s as a diagnostic tool for hepatocellular carcinoma in a hyper endemic HIV setting, KwaZulu-Natal, South Africa: a case control study protocol focusing on viral etiology

A wide range of studies has investigated the diagnostic proficiency of extracellular microRNAs (miRNAs) in hepatocellular cancer (HCC). HCC is expected to increase in Sub-Saharan Africa (SSA), due to endemic l...

K. Sartorius, B. Sartorius, A. Kramvis, E. Singh, A. Turchinovich… in BMC Cancer (2017)

Article

Interference in transcription of overexpressed genes by promoter-proximal downstream sequences

Despite a high sequence homology among four human RNAi-effectors Argonaute proteins and their coding sequences, the efficiency of ectopic overexpression of AGO3 and AGO4 coding sequences in human cells is grea...

A. Turchinovich, H. M. Surowy, A. G. Tonevitsky, B. Burwinkel in Scientific Reports (2016)

Article

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF...

D Agarwal, S Pineda, K Michailidou, J Herranz, G Pita… in British Journal of Cancer (2014)

Article

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk

Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor recep...

K N Stevens, M Garcia-Closas, Z Fredericksen, M Kosel… in British Journal of Cancer (2011)

Article

Inhibition of Id proteins by a peptide aptamer induces cell-cycle arrest and apoptosis in ovarian cancer cells

Inhibitors of DNA-binding proteins (Id1-4), lacking the basic DNA-binding domain, function as dominant inhibitors of cell-cycle regulators. Overexpression of Id proteins promotes cancer cell proliferation and ...

D S Mern, J Hasskarl, B Burwinkel in British Journal of Cancer (2010)

Article

Multicentre study of CASP8 polymorphisms in breast cancer

N Shephard, I Brock, N Camp, L Canon-Albright, B Frank… in Breast Cancer Research (2008)

Article

The rare ERBB2 variant Ile654Val is associated with an increased familial breast cancer risk

B Frank, K Hemminki, M Wirtenberger, JL Bermejo, P Bugert… in Breast Cancer Research (2005)

Article

Association of NCOA3 (AIB1) polymorphisms with breast cancer risk

B Burwinkel, M Wirtenberger, B Frank, R Klaes, RK Schmutzler… in Breast Cancer Research (2005)

Article

40^th EASD Annual Meeting of the European Association for the Study of Diabetes

M. Veitenhansl, K. Stegner, F.-X. Hierl, C. Dieterle, H. Feldmeier, B. Gutt… in Diabetologia (2004)