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Article
Open AccessSymbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon
Intestinal microbiota-derived metabolites have biological importance for the host. Polyamines, such as putrescine and spermidine, are produced by the intestinal microbiota and regulate multiple biological proc...
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Article
Open AccessEarly-stage T1b adenocarcinoma arising in the remnant cystic duct after laparoscopic cholecystectomy: a case report and literature review
The cystic duct has been included in the staging classification scheme for gallbladder cancer since the 2010 publication of the AJCC Cancer Staging Manual (7th edition). To our knowledge, only seven other case...
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Article
Open AccessUpregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice
Prevention of quality of life (QOL) deterioration is associated with the inhibition of geriatric diseases and the regulation of brain function. However, no substance is known that prevents the aging of both bo...
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Endoscopic Diagnosis of Barrett’s Esophagus and Esophageal Adenocarcinomas
The use of methylene blue and acetic acid in magnifying endoscopic diagnosis of intestinal metaplasia in Barrett’s esophagus has been reported previously. Recently, the use of acetic acid or narrow-band imagin...
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Article
Regular arrangement of collecting venules (RAC): a characteristic endoscopic feature of Helicobacter pylori-negative normal stomach and its relationship with esophago-gastric adenocarcinoma
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Article
Increased hTR Expression During Transition from Adenoma to Carcinoma Is Not Associated with Promoter Methylation
Human telomerase RNA component (hTR) expression, which increases in the majority of cancer cells with an acquisition of telomerase activity, was concomitantly evaluated with methylation status and human telomera...
