4 Result(s)

Article

The association of hypoglycemia with outcome of critically ill children in relation to nutritional and blood glucose control strategies

Withholding parenteral nutrition (PN) until one week after PICU admission facilitated recovery from critical illness and protected against emotional and behavioral problems 4 years later. However, the interven...

Jan Gunst, Astrid De Bruyn, An Jacobs, Lies Langouche, Inge Derese… in Critical Care (2023)

Article

Impact of tight glucose control on circulating 3-hydroxybutyrate in critically ill patients

Recent evidence suggests a potentially protective effect of increasing ketone body availability via accepting low macronutrient intake early after onset of critical illness. The impact of blood glucose control...

Jan Gunst, Astrid De Bruyn, Michael P. Casaer, Sarah Vander Perre… in Critical Care (2021)

Article

Impact of withholding early parenteral nutrition in adult critically ill patients on ketogenesis in relation to outcome

Astrid De Bruyn, Lies Langouche, Sarah Vander Perre, Jan Gunst… in Critical Care (2021)

Article

Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit

In critically ill children, omitting early use of parenteral nutrition (late-PN versus early-PN) reduced infections, accelerated weaning from mechanical ventilation, and shortened PICU stay. We hypothesized th...

Astrid De Bruyn, Jan Gunst, Chloë Goossens, Sarah Vander Perre… in Critical Care (2020)