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Article
Open AccessBrain asymmetries from mid- to late life and hemispheric brain age
The human brain demonstrates structural and functional asymmetries which have implications for ageing and mental and neurological disease development. We used a set of magnetic resonance imaging (MRI) metrics ...
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Chapter and Conference Paper
Brain Tumor Segmentation from Multiparametric MRI Using a Multi-encoder U-Net Architecture
This paper describes our submission to Task 1 of the RSNA-ASNR-MICCAI Brain Tumor Segmentation (BraTS) Challenge 2021, where the goal is to segment brain glioblastoma sub-regions in multi-parametric MRI scans....
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Article
Open Access1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Hu...
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Article
Open AccessAutomated segmentation of endometrial cancer on MR images using deep learning
Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume t...
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Chapter and Conference Paper
Deep Convolutional Neural Networks in Application to Kidney Segmentation in the DCE-MR Images
This paper evaluates three convolutional neural network architectures – U-Net, SegNet, and Fully Convolutional (FC) DenseNets – in application to kidney segmentation in the dynamic contrast-enhanced magnetic r...
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Article
Open AccessBrain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
The hippocampus is a heterogeneous structure, comprising histologically distinguishable subfields. These subfields are differentially involved in memory consolidation, spatial navigation and pattern separation...
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Article
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Prior to and following the publication of this article the authors noted that the complete list of authors was not included in the main article and was only present in Supplementary Table 1. The author list in...
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Article
Open AccessDose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Carriers of large recurrent copy number variants (CNVs) have a higher risk of develo** neurodevelopmental disorders. The 16p11.2 distal CNV predisposes carriers to e.g., autism spectrum disorder and schizoph...
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Article
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Common risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life. Using struct...
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Article
Open AccessPost-adolescent developmental changes in cortical complexity
Post-adolescence is known to be a period of general maturation and development in the human brain. In brain imaging, volumetric and morphologic cortical grey-matter changes can easily be assessed, but the anal...
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Article
Local/non-local regularized image segmentation using graph-cuts
Multispectral, multichannel, or time series image segmentation is important for image analysis in a wide range of applications. Regularization of the segmentation is commonly performed using local image infor...
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Article
Open AccessCellSegm - a MATLAB toolbox for high-throughput 3D cell segmentation
The application of fluorescence microscopy in cell biology often generates a huge amount of imaging data. Automated whole cell segmentation of such data enables the detection and analysis of individual cells, ...
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Article
Registration of FA and T1-Weighted MRI Data of Healthy Human Brain Based on Template Matching and Normalized Cross-Correlation
In this work, we propose a new approach for three-dimensional registration of MR fractional anisotropy images with T1-weighted anatomy images of human brain. From the clinical point of view, this accurate core...
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Chapter and Conference Paper
Hypothesis Generation by Interactive Visual Exploration of Heterogeneous Medical Data
High dimensional, heterogeneous datasets are challenging for domain experts to analyze. A very large number of dimensions often pose problems when visual and computational analysis tools are considered. Analys...
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Article
Open AccessOn consciousness, resting state fMRI, and neurodynamics
During the last years, functional magnetic resonance imaging (fMRI) of the brain has been introduced as a new tool to measure consciousness, both in a clinical setting and in a basic neurocognitive research. M...
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Article
Open AccessCorrelations between measures of executive attention and cortical thickness of left posterior middle frontal gyrus - a dichotic listening study
The frontal lobe has been associated to a wide range of cognitive control functions and is also vulnerable to degeneration in old age. A recent study by Thomsen and colleagues showed a difference between a you...
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Article
Open AccessHippocampal volumes are important predictors for memory function in elderly women
Normal aging involves a decline in cognitive function that has been shown to correlate with volumetric change in the hippocampus, and with genetic variability in the APOE-gene. In the present study we utilize ...
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Article
Shape-Adaptive DCT for Denoising of 3D Scalar and Tensor Valued Images
During the last ten years or so, diffusion tensor imaging has been used in both research and clinical medical applications. To construct the diffusion tensor images, a large set of direction sensitive magnetic...
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Chapter and Conference Paper
Flow Quantification from 2D Phase Contrast MRI in Renal Arteries Using Clustering
We present an approach based on clustering to segment renal arteries from 2D PC Cine MR images to measure blood velocity and flow. Such information are important in grading renal artery stenosis and support th...
