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  1. Article

    Open Access

    Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression

    Women with a cervicovaginal microbiota dominated by Lactobacillus spp. are at reduced risk of acquiring sexually transmitted infections including HIV, but the biological mechanisms involved remain poorly defined....

    David Jose Delgado-Diaz, Brianna Jesaveluk, Joshua A. Hayward, David Tyssen in Microbiome (2022)

  2. Article

    Open Access

    Correction to: Microbial function and genital inflammation in young South African women at high risk of HIV infection

    Arghavan Alisoltani, Monalisa T. Manhanzva, Matthys Potgieter in Microbiome (2022)

  3. Article

    Open Access

    Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

    The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (...

    Raquel Viana, Sikhulile Moyo, Daniel G. Amoako, Houriiyah Tegally in Nature (2022)

  4. Article

    Detection of a SARS-CoV-2 variant of concern in South Africa

    Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating conditions for substantial evolutionary changes to the virus1,2. Here we describe a newly arisen lineage of SARS-CoV-2 (des...

    Houriiyah Tegally, Eduan Wilkinson, Marta Giovanetti, Arash Iranzadeh in Nature (2021)

  5. Article

    Open Access

    Microbial function and genital inflammation in young South African women at high risk of HIV infection

    Female genital tract (FGT) inflammation is an important risk factor for HIV acquisition. The FGT microbiome is closely associated with inflammatory profile; however, the relative importance of microbial activi...

    Arghavan Alisoltani, Monalisa T. Manhanzva, Matthys Potgieter in Microbiome (2020)

  6. No Access

    Chapter

    Bacterial Pan-Genomics

    Due to their tendency to have a high recombination rate, bacterial genomes are highly diverse across different strains. This diversity may even be in the form of the presence or absence of entire genes; theref...

    Arash Iranzadeh, Nicola Jane Mulder in Microbial Genomics in Sustainable Agroecosystems (2019)