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Open AccessDistinct grey and white matter changes are associated with the phenomenology of visual hallucinations in Lewy Body Disease
Visual hallucinations in Lewy body disease (LBD) can be differentiated based on phenomenology into minor phenomena (MVH) and complex hallucinations (CVH). MVH include a variety of phenomena, such as illusions,...
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Article
Blurred lines: bilateral optic perineuritis mimicking idiopathic intracranial hypertension
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Botulinum toxin in clinical practice: state of the art of administration provisions in Italy
Botulinum neurotoxin type A is a remarkable therapeutic approach for muscle hyperactivity syndromes, pain, and related disorders. Despite its wide application in neurology, there is a poor knowledge on deliver...
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Article
Open AccessThe Cerebellum in Drug-naive Children with Tourette Syndrome and Obsessive–Compulsive Disorder
Tourette syndrome (TS) and obsessive–compulsive disorder (OCD) are two neurodevelopmental disorders characterized by repetitive behaviors. Our recent study in drug-naive children with TS and OCD provided evide...
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Article
Open AccessAxial impairment and falls in Parkinson’s disease: 15 years of subthalamic deep brain stimulation
In this retrospective study, we longitudinally analyzed axial impairment and falls in people with Parkinson’s disease (PD) and subthalamic nucleus deep brain stimulation (STN-DBS). Axial scores and falling fre...
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Article
Open AccessVisual hallucinations in Lewy body disease: pathophysiological insights from phenomenology
Visual hallucinations (VH) in Lewy body disease (LBD) have a heterogenous phenomenology classified into minor phenomena (MVH) and complex hallucinations (CVH). Mechanisms underpinning VH and their temporal asp...
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Article
Environmental conditions as proximate cues of predation risk inducing defensive response in Daphnia pulex
Daphnia pulex from a pond in Northern Italy shows four distinct defensive morphotypes, varying in the number, location and thickness of neckteeth, as the results of phenotypic plasticity. Because the frequency of...
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Article
Open AccessRoundup causes embryonic development failure and alters metabolic pathways and gut microbiota functionality in non-target species
Research around the weedkiller Roundup is among the most contentious of the twenty-first century. Scientists have provided inconclusive evidence that the weedkiller causes cancer and other life-threatening dis...
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Article
Aberrant functional connectivity in patients with Parkinson’s disease and freezing of gait: a within- and between-network analysis
Freezing of gait (FOG) is a disabling motor symptom that affects patients with Parkinson’s disease (PD). MRI-based evidence suggest that multiple brain structures are involved in the occurrence of FOG. We inve...
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Article
Open AccessDetecting cortical circuits resonant to high-frequency oscillations in the human primary motor cortex: a TMS-tACS study
Corticospinal volleys evoked by transcranial magnetic stimulation (TMS) over the primary motor cortex (M1) consist of high-frequency bursts (≈667 and ≈333 Hz). However, intracortical circuits producing such co...
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Article
Promoting post-stroke recovery through focal or whole body vibration: criticisms and prospects from a narrative review
Several focal muscle vibration (fMV) and whole body vibration (WBV) protocols have been designed to promote brain reorganization processes in patients with stroke. However, whether fMV and WBV should be consid...
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Article
Open AccessIntronic ATTTC repeat expansions in STARD7 in familial adult myoclonic epilepsy linked to chromosome 2
Familial Adult Myoclonic Epilepsy (FAME) is characterised by cortical myoclonic tremor usually from the second decade of life and overt myoclonic or generalised tonic-clonic seizures. Four independent loci hav...
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Abnormal Cerebellar Connectivity Patterns in Patients with Parkinson’s Disease and Freezing of Gait
In this study, we aimed to evaluate the importance of cerebellum in freezing of gait (FOG) pathophysiology. Due to the fundamental role of the cerebellum in posture and gait control, we examined cerebellar str...
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Open AccessTransgenerational response to early spring warming in Daphnia
Temperature and photoperiod regulate key fitness traits in plants and animals. However, with temperature increase due to global warming, temperature cue thresholds are experienced at shorter photoperiods, disr...
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Polymorphisms in predator induced defences of coexisting Daphnia pulex and D. longispina
A comparison of juvenile predator-avoidance polymorphisms of Daphnia pulex and D. longispina in a shallow water body of Northern Italy is reported. The presence of the Chaoborus larvae resulted in juvenile adapti...
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Freezing of gait in Parkinson’s disease: gray and white matter abnormalities
Freezing of gait (FOG) is a disabling disorder that often affects Parkinson’s disease (PD) patients in advanced stages of the disease. To study structural gray matter (GM) and white matter (WM) changes in PD p...
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Article
MRI gray and white matter measures in progressive supranuclear palsy and corticobasal syndrome
We evaluated MRI measures of gray and white matter damages in 19 patients with progressive supranuclear palsy (PSP), 11 with corticobasal syndrome (CBS), and 14 healthy subjects (HS) to differentiate patients ...