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Open AccessDiffusive tail anchorage determines velocity and force produced by kinesin-14 between crosslinked microtubules
Form and function of the mitotic spindle depend on motor proteins that crosslink microtubules and move them relative to each other. Among these are kinesin-14s, such as Ncd, which interact with one microtubule...
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Changes in microtubule overlap length regulate kinesin-14-driven microtubule sliding
Microtubule sliding driven by kinesin-14 HSET is regulated by a feedback mechanism. When microtubules start sliding apart, HSET molecules are retained in the shortening overlap, which leads to an HSET-density-...
