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  1. Article

    Open Access

    Nutrition or nature: using elementary flux modes to disentangle the complex forces sha** prokaryote pan-genomes

    Microbial pan-genomes are shaped by a complex combination of stochastic and deterministic forces. Even closely related genomes exhibit extensive variation in their gene content. Understanding what drives this ...

    Daniel R. Garza, F. A. Bastiaan von Meijenfeldt, Bram van Dijk… in BMC Ecology and Evolution (2022)

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  2. Article

    Open Access

    G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

    G protein-coupled receptor (GPR)35 is highly expressed in the gastro-intestinal tract, predominantly in colon epithelial cells (CEC), and has been associated with inflammatory bowel diseases (IBD), suggesting ...

    Annemarie Boleij, Payam Fathi, William Dalton, Ben Park… in Communications Biology (2021)

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    Reference Work Entry In depth

    Colorectal Cancer-Associated Microbiota

    Harold Tjalsma, Bas E. Dutilh, Annemarie Boleij… in Encyclopedia of Metagenomics (2015)

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    Living Reference Work Entry In depth

    Colorectal Cancer-Associated Microbiota

    Harold Tjalsma, Bas E. Dutilh, Annemarie Boleij… in Encyclopedia of Metagenomics

  5. No Access

    Article

    A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects

    Recent high-throughput sequencing studies have provided a first glimpse of the microbiome associated with late-stage colorectal cancer. In this Opinion article, Tjalsma and colleagues present a driver–passenge...

    Harold Tjalsma, Annemarie Boleij, Julian R. Marchesi… in Nature Reviews Microbiology (2012)