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Article
Open AccessThe gut microbiome of exudivorous marmosets in the wild and captivity
Mammalian captive dietary specialists like folivores are prone to gastrointestinal distress and primate dietary specialists suffer the greatest gut microbiome diversity losses in captivity compared to the wild...
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Article
Open AccessGeographically dispersed zoonotic tuberculosis in pre-contact South American human populations
Previous ancient DNA research has shown that Mycobacterium pinnipedii, which today causes tuberculosis (TB) primarily in pinnipeds, infected human populations living in the coastal areas of Peru prior to European...
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Article
Open AccessGenomic skimming and nanopore sequencing uncover cryptic hybridization in one of world’s most threatened primates
The Brazilian buffy-tufted-ear marmoset (Callithrix aurita), one of the world’s most endangered primates, is threatened by anthropogenic hybridization with exotic, invasive marmoset species. As there are few gene...
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Article
Open AccessMitogenomic phylogeny of Callithrix with special focus on human transferred taxa
Callithrix marmosets are a relatively young primate radiation, whose phylogeny is not yet fully resolved. These primates are naturally para- and allopatric, but three species with highly invasive potential have b...
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Article
Open AccessDifferential DNA methylation of vocal and facial anatomy genes in modern humans
Changes in potential regulatory elements are thought to be key drivers of phenotypic divergence. However, identifying changes to regulatory elements that underlie human-specific traits has proven very challeng...
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Article
Open AccessMetagenomic analysis of dental calculus in ancient Egyptian baboons
Dental calculus, or mineralized plaque, represents a record of ancient biomolecules and food residues. Recently, ancient metagenomics made it possible to unlock the wealth of microbial and dietary information ...
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Article
Open AccessOral microbiome diversity in chimpanzees from Gombe National Park
Historic calcified dental plaque (dental calculus) can provide a unique perspective into the health status of past human populations but currently no studies have focused on the oral microbial ecosystem of oth...
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Article
Open AccessIn-solution Y-chromosome capture-enrichment on ancient DNA libraries
As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach—in-solution capture-enrichment—retrieves sequen...
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Article
Open AccessDifferential preservation of endogenous human and microbial DNA in dental calculus and dentin
Dental calculus (calcified dental plaque) is prevalent in archaeological skeletal collections and is a rich source of oral microbiome and host-derived ancient biomolecules. Recently, it has been proposed that ...
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Article
Open AccessA composite genome approach to identify phylogenetically informative data from next-generation sequencing
Improvements in sequencing technology now allow easy acquisition of large datasets; however, analyzing these data for phylogenetics can be challenging. We have developed a novel method to rapidly obtain homolo...
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Article
Open AccessRapid evolution of BRCA1 and BRCA2in humans and other primates
The maintenance of chromosomal integrity is an essential task of every living organism and cellular repair mechanisms exist to guard against insults to DNA. Given the importance of this process, it is expected...
