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Open AccessGene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics
Periodontitis is a highly prevalent chronic inflammatory disease of the periodontium, leading ultimately to tooth loss. In order to characterize the gene expression of periodontitis-affected gingival tissue, w...
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Article
Open AccessCorrection: Corrigendum: An automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries
Scientific Reports 6: Article number: 37137; published online: 16 November 2016; updated: 13 March 2017 This Article contains errors in Figure 6c. The Pearson correlation values for the automated and manually ...
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Article
Open AccessAn automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries
Sequencing the nucleic acid content of individual cells or specific biological samples is becoming increasingly common. This drives the need for robust, scalable and automated library preparation protocols. Fu...
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Open AccessEffects by periodontitis on pristane-induced arthritis in rats
An infection-immune association of periodontal disease with rheumatoid arthritis has been suggested. This study aimed to investigate the effect of pre-existing periodontitis on the development and the immune/i...
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Article
Open AccessTranscriptome analysis reveals mucin 4 to be highly associated with periodontitis and identifies pleckstrin as a link to systemic diseases
The multifactorial chronic inflammatory disease periodontitis, which is characterized by destruction of tooth-supporting tissues, has also been implicated as a risk factor for various systemic diseases. Althou...