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We report the findings from 4437 individuals (3219 patients and 1218 relatives) who have been analyzed by whole genome sequencing (WGS) at the Genomic Medicine Center Karolinska-Rare Diseases (GMCK-RD) since m...
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Open AccessAutomation of Spatial Transcriptomics library preparation to enable rapid and robust insights into spatial organization of tissues
Interest in studying the spatial distribution of gene expression in tissues is rapidly increasing. Spatial Transcriptomics is a novel sequencing-based technology that generates high-throughput information on t...
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Open AccessGene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics
Periodontitis is a highly prevalent chronic inflammatory disease of the periodontium, leading ultimately to tooth loss. In order to characterize the gene expression of periodontitis-affected gingival tissue, w...
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Open AccessCorrection: Corrigendum: An automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries
Scientific Reports 6: Article number: 37137; published online: 16 November 2016; updated: 13 March 2017 This Article contains errors in Figure 6c. The Pearson correlation values for the automated and manually ...
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Open AccessAn automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries
Sequencing the nucleic acid content of individual cells or specific biological samples is becoming increasingly common. This drives the need for robust, scalable and automated library preparation protocols. Fu...
