15 Result(s)

Article

Healthcare resource utilization and costs associated with psychiatric comorbidities in pediatric patients with attention-deficit/hyperactivity disorder: a claims-based case-cohort study

Attention-deficit/hyperactivity disorder (ADHD) has been shown to pose considerable clinical and economic burden; however, research quantifying the excess burden attributable to common psychiatric comorbiditie...

Jeff Schein, Martin Cloutier… in Child and Adolescent Psychiatry and Mental… (2024)

Article

Two single arm trials of AKL-T01, a digital therapeutic for adolescents and adults with ADHD

Inattention symptoms represent a key driver of functional impairment in ADHD and often persist into adolescence and adulthood, underscoring a need for novel treatments targeting attentional control. We evaluat...

Caitlin A. Stamatis, Deborah N. Farlow, Catherine Mercaldi… in npj Mental Health Research (2024)

Article

Risk factors associated with newly diagnosed attention-deficit/hyperactivity disorder in adults: a retrospective case-control study

Knowledge of risk factors for attention-deficit/hyperactivity disorder (ADHD) may facilitate early diagnosis; however, studies examining a broad range of potential risk factors for ADHD in adults are limited. ...

Jeff Schein, Martin Cloutier, Marjolaine Gauthier-Loiselle… in BMC Psychiatry (2023)

Article

Treatment Patterns Among Patients with Attention-Deficit/Hyperactivity Disorder and Comorbid Anxiety and/or Depression in the United States: A Retrospective Claims Analysis

Patients with attention-deficit/hyperactivity disorder (ADHD) often have psychiatric comorbidities that may confound diagnosis and affect treatment outcomes and costs. The current study described treatment pat...

Jeff Schein, Ann Childress, Patrick Gagnon-Sanschagrin… in Advances in Therapy (2023)

Article

Authors’ Reply to Singh and Balasundaram: Comment on “A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Efficacy and Safety of Viloxazine Extended-Release Capsules in Adults with Attention-Deficit/Hyperactivity Disorder”

Azmi Nasser, Joseph T. Hull, Tesfaye Liranso, Nicholas Fry, Andrew J. Cutler… in CNS Drugs (2022)

Article

Reasons for Treatment Changes in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Chart Review Study

This study aimed to examine the reasons underlying treatment changes among pediatric patients with attention-deficit/hyperactivity disorder (ADHD).

Jeff Schein, Martin Cloutier, Marjolaine Gauthier-Loiselle… in Advances in Therapy (2022)

Article

Treatment patterns among children and adolescents with attention-deficit/hyperactivity disorder in the United States – a retrospective claims analysis

Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral disorder affecting approximately 10.0% of children and 6.5% of adolescents in the United States (US). A comprehensive assessment of t...

Jeff Schein, Ann Childress, Julie Adams, Patrick Gagnon-Sanschagrin… in BMC Psychiatry (2022)

Article

A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Efficacy and Safety of Viloxazine Extended-Release Capsules in Adults with Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder is a neurodevelopmental disorder that typically begins in childhood and often persists into adulthood. Recent phase III trials have demonstrated the efficacy and safety...

Azmi Nasser, Joseph T. Hull, Soumya A. Chaturvedi, Tesfaye Liranso… in CNS Drugs (2022)

Article

Reasons for treatment changes in adults with attention-deficit/hyperactivity disorder: a chart review study

Adults with attention-deficit hyperactivity disorder (ADHD) often cycle through multiple treatments for reasons that are not well documented. This study analyzed the reasons underlying treatment changes among ...

Jeff Schein, Ann Childress, Martin Cloutier, Urvi Desai, Andi Chin… in BMC Psychiatry (2022)

Article

Effectiveness of a digital therapeutic as adjunct to treatment with medication in pediatric ADHD

STARS-Adjunct was a multicenter, open-label effectiveness study of AKL-T01, an app and video-game-based treatment for inattention, as an adjunct to pharmacotherapy in 8–14-year-old children with attention-defi...

Scott H. Kollins, Ann Childress, Andrew C. Heusser, Jacqueline Lutz in npj Digital Medicine (2021)

Article

Efficacy of Methylphenidate Hydrochloride Extended-Release Capsules (Aptensio XR™) in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Phase III, Randomized, Double-Blind Study

Psychostimulants remain first-line treatment options for the management of attention-deficit/hyperactivity disorder (ADHD). A multilayer extended-release bead methylphenidate capsule (provisional name Aptensio...

Sharon B. Wigal, Earl Nordbrock, Akwete L. Adjei, Ann Childress… in CNS Drugs (2015)