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Article
Open AccessHepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice
Schistosomiasis is a parasitic disease affecting more than 250 million people worldwide. The transcription factor c-Jun, which is induced in S. mansoni infection-associated liver disease, can promote hepatocyte s...
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Article
Open AccessMultidimensional assessment of infant, parent and staff outcomes during a family centered care enhancement project in a tertiary neonatal intensive care unit: study protocol of a longitudinal cohort study
The therapeutic advances and progress in the care for preterm infants have enabled the regular survival of very immature infants. However, the high burden of lifelong sequelae following premature delivery cons...
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Article
Open AccessPeroxisomes during postnatal development of mouse endocrine and exocrine pancreas display cell-type- and stage-specific protein composition
Peroxisomal dysfunction unhinges cellular metabolism by causing the accumulation of toxic metabolic intermediates (e.g. reactive oxygen species, very -chain fatty acids, phytanic acid or eicosanoids) and the d...
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Article
Open AccessClinical characteristics of patients with familial idiopathic pulmonary fibrosis (f-IPF)
The aim of this study was to analyze the relative frequency, clinical characteristics, disease onset and progression in f-IPF vs. sporadic IPF (s-IPF).
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Article
Open AccessGene expression profiling at birth characterizing the preterm infant with early onset infection
Early onset infection (EOI) in preterm infants <32 weeks gestational age (GA) is associated with a high mortality rate and the development of severe acute and long-term complications. The pathophysiology of EO...
