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    Chapter

    Evolutionary Dynamics of a Population of Cells with a Toxin Suppressor Gene

    Environmental changes are known to trigger evolutionary changes, e.g. by favoring higher mutation rates. We study the evolutionary dynamics of a delayed stochastic genetic circuit using a simulator developed f...

    Antti Häkkinen, Fred G. Biddle in Transactions on Computational Systems Biol… (2011)

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    Chapter and Conference Paper

    Modeling and Engineering Promoters with Pre-defined RNA Production Dynamics in Escherichia Coli

    Recent developments in live-cell time-lapse microscopy and signal processing methods for single-cell, single-RNA detection now allow characterizing the in vivo dynamics of RNA production of Escherichia coli promo...

    Samuel M. D. Oliveira, Mohamed N. M. Bahrudeen in Computational Methods in Systems Biology (2018)