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    DNA Origami-Based Single-Molecule Force Spectroscopy and Applications

    Over the last years, single-molecule force spectroscopy provided insights into the intricate connection between mechanical stimuli and biochemical signaling. The underlying molecular mechanisms were uncovered ...

    Kevin Kramm, Tim Schröder, Andrés Manuel Vera in Single Molecule Analysis (2024)

  2. Article

    Open Access

    DNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability

    The TATA-binding protein (TBP) and a transcription factor (TF) IIB-like factor are important constituents of all eukaryotic initiation complexes. The reason for the emergence and strict requirement of the addi...

    Kevin Kramm, Tim Schröder, Jerome Gouge, Andrés Manuel Vera in Nature Communications (2020)

  3. Article

    Publisher Correction: Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

    This paper was originally published under standard Springer Nature copyright. As of the date of this correction, the Analysis is available online as an open-access paper with a CC-BY license. No other part of ...

    Björn Hellenkamp, Sonja Schmid, Olga Doroshenko, Oleg Opanasyuk in Nature Methods (2018)

  4. Article

    Open Access

    Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

    Single-molecule Förster resonance energy transfer (smFRET) is increasingly being used to determine distances, structures, and dynamics of biomolecules in vitro and in vivo. However, generalized protocols and F...

    Björn Hellenkamp, Sonja Schmid, Olga Doroshenko, Oleg Opanasyuk in Nature Methods (2018)