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DNA Origami-Based Single-Molecule Force Spectroscopy and Applications
Over the last years, single-molecule force spectroscopy provided insights into the intricate connection between mechanical stimuli and biochemical signaling. The underlying molecular mechanisms were uncovered ...
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Article
Open AccessDNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability
The TATA-binding protein (TBP) and a transcription factor (TF) IIB-like factor are important constituents of all eukaryotic initiation complexes. The reason for the emergence and strict requirement of the addi...
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Publisher Correction: Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study
This paper was originally published under standard Springer Nature copyright. As of the date of this correction, the Analysis is available online as an open-access paper with a CC-BY license. No other part of ...
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Open AccessPrecision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study
Single-molecule Förster resonance energy transfer (smFRET) is increasingly being used to determine distances, structures, and dynamics of biomolecules in vitro and in vivo. However, generalized protocols and F...