-
Chapter
Fundamental Structure, Composition and Cutting-Edge Applications of Polysaccharides in the Contemporary Context
With the advent of science and technology, study on polysaccharides has become convenient and easier to unravel several potential facts about the biomolecule. The basic architecture of polysaccharides derived ...
-
Article
Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma
Head and neck squamous cell carcinoma (HNSCC) includes a subset of cancers driven by human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive and HPV-negative oropharyngeal tumo...
-
Chapter
Phylogenomics, Microbiome and Morphological Insights of Truffles: The Tale of a Sensory Stimulating Ectomycorrhizal Filamentous Fungus
Truffles are generally considered as subterraneous ascomycete, capable of forming ectomycorrhizas with plant roots via symbiosis. The fruiting body of truffles are widely appreciated around the world for its d...
-
Article
Partial EMT in head and neck cancer biology: a spectrum instead of a switch
Our understanding of epithelial-to-mesenchymal transition (EMT) has slowly evolved from a simple two state, binary model to a multi-step, dynamic continuum of epithelial-to-mesenchymal plasticity, with metasta...
-
Article
Open AccessMesoporous silica based recyclable probe for colorimetric detection and separation of ppb level Hg2+ from aqueous medium
Functional mesoporous silica probes, MCM-TFM and SBA-TFM, have been synthesized with varying pore sizes and having S-donor sites judiciously selected to bind soft metal centers. The soft S-donor centers are contr...
-
Article
Open AccessAnti-hepatitis B virus (HBV) response of imiquimod based toll like receptor 7 ligand in hbv-positive human hepatocelluar carcinoma cell line
Toll like receptors (TLRs) play an important role in innate immunity and various studies suggest that TLRs play a crucial role in pathogenesis of hepatitis B virus (HBV) infection. The present study aims in lo...
-
Article
Open AccessHepatitis B virus X protein mediated suppression of miRNA-122 expression enhances hepatoblastoma cell proliferation through cyclin G1-p53 axis
Hepatitis B virus (HBV) X protein (HBx) reported to be associated with pathogenesis of hepatocellular carcinoma (HCC) and miR-122 expression is down regulated in HCC. Previous studies reported miR-122 targets ...
-
Article
Open AccessTumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by Hepatitis B virus X protein in malignant hepatocytes
Hepatitis B Virus (HBV) X protein (HBx) is known to be involved in the initiation and progression of hepatocellular carcinoma (HCC) through modulation of host gene response. Alterations in miRNA expressions ar...
