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    Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production

    Mice lacking activity of the kinase MEKK1 ('Map3k1ΔKD' mice) have defective activation of the kinase Jnk and increased production of T helper type 2 cytokines after T cell receptor ligation. Here we show that Map...

    Ewen Gallagher, Thomas Enzler, Atsushi Matsuzawa, Amy Anzelon-Mills in Nature Immunology (2007)