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  1. Article

    Open Access

    The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome

    Estrogens play a pivotal role in the initiation and progression of breast cancer. The genes that mediate these processes are not fully defined, but potentially include the known mammary oncogene MYC. Characteriza...

    Alison J Butt, C Marcelo Sergio, Claire K Inman, Luke R Anderson… in Breast Cancer Research (2008)

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  2. No Access

    Article

    EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer

    EDD (E3 isolated by differential display), located at chromosome 8q22.3, is the human orthologue of the Drosophila melanogaster tumour suppressor gene ‘hyperplastic discs’ and encodes a HECT domain E3 ubiquitin p...

    Jennifer L Clancy, Michelle J Henderson, Amanda J Russell, David W Anderson… in Oncogene (2003)

  3. No Access

    Article

    Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs

    Use of the differential display technique to isolate progestin-regulated genes in T-47D human breast cancer cells led to identification of a novel gene, EDD. The cDNA sequence contains a 2799 amino acid open r...

    Michelle J Callaghan, Amanda J Russell, Erica Woollatt, Grant R Sutherland… in Oncogene (1998)