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Article
Open AccessStereotactic radiotherapy of nodal oligometastases from prostate cancer: a prisma-compliant systematic review
Androgen deprivation therapy (ADT) is the standard treatment of metastatic prostate cancer (PCa). However, metastases-directed therapies can delay the initiation or switch of systemic treatments and allow loca...
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Article
Open AccessTP53 drives abscopal effect by secretion of senescence-associated molecular signals in non-small cell lung cancer
Recent developments in abscopal effect strongly support the use of radiotherapy for the treatment of metastatic disease. However, deeper understanding of the molecular mechanisms underlying the abscopal effect...
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Article
Open AccessModeling neoplastic disease with spheroids and organoids
Cancer is a complex disease in which both genetic defects and microenvironmental components contribute to the development, progression, and metastasization of disease, representing major hurdles in the identif...