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Article
Reirradiation on spine metastases: an Italian survey on behalf of palliative care and reirradiation study groups of Italian association of radiotherapy and clinical oncology (AIRO)
This survey derived from the collaboration between the Palliative Care and Reirradiation Study Groups of the Italian Association of Radiotherapy and Clinical Oncology (AIRO). Its aim was to obtain a real “snap...
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Article
Open AccessStereotactic radiotherapy of nodal oligometastases from prostate cancer: a prisma-compliant systematic review
Androgen deprivation therapy (ADT) is the standard treatment of metastatic prostate cancer (PCa). However, metastases-directed therapies can delay the initiation or switch of systemic treatments and allow loca...
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Article
Open AccessTP53 drives abscopal effect by secretion of senescence-associated molecular signals in non-small cell lung cancer
Recent developments in abscopal effect strongly support the use of radiotherapy for the treatment of metastatic disease. However, deeper understanding of the molecular mechanisms underlying the abscopal effect...
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Article
Electrochemotherapy of skin metastases from breast cancer: a systematic review
Skin metastases occur in 5–30% of breast cancer (BC) patients. Standard treatments include systemic therapies (chemotherapy, endocrine therapy, and immunotherapy) and local treatments (surgery and radiotherapy...
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Article
Systematic review of stereotactic body radiotherapy for nodal metastases
The aim of this analysis was to assess the efficacy of stereotactic body radiotherapy (SBRT) in terms of local control (LC) and progression-free survival (PFS) in patients with lymph node metastases (NMs) from...
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Article
Open AccessModeling neoplastic disease with spheroids and organoids
Cancer is a complex disease in which both genetic defects and microenvironmental components contribute to the development, progression, and metastasization of disease, representing major hurdles in the identif...
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Article
Radiotherapy in palliation of thoracic tumors: a phase I–II study (SHARON project)
The main clinical goal for patients with advanced or metastatic thoracic cancer is palliation of tumor-related symptoms and improvement of quality of life. The aim of this phase I–II trial was to define the ma...
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Article
Efficacy and safety of 3D-conformal half body irradiation in patients with multiple bone metastases
Half-body irradiation (HBI) represented a standard treatment for multiple painful bone metastases (BMs). However, its use has progressively reduced due to the associated toxicity rates. The aim of this paper w...