4 Result(s)

Article

High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria

microRNAs (miRNAs) are critical for neuronal function and their dysregulation is repeatedly observed in neurodegenerative diseases. Here, we implemented high content image analysis for investigating the impact...

Tal Yardeni, Raquel Fine, Yuvraj Joshi, Tal Gradus-Pery, Noga Kozer… in Scientific Reports (2018)

Article

PRMT1 inhibition induces differentiation of colon cancer cells

Differentiation therapy has been recently revisited as a prospective approach in cancer therapy by targeting the aberrant growth, and repairing the differentiation and cell death programs of cancer cells. Howe...

Alexander Plotnikov, Noga Kozer, Galit Cohen, Silvia Carvalho… in Scientific Reports (2020)

Article

Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase

Government-sanctioned use of nerve agents (NA) has escalated dramatically in recent years. Oxime reactivators of organophosphate (OP)-inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) serv...

Gabriel Amitai, Alexander Plotnikov, Shira Chapman, Shlomi Lazar… in Communications Biology (2021)

Article

Correction: A duplex structure of SARM1 octamers stabilized by a new inhibitor

Tami Khazma, Yarden Golan-Vaishenker… in Cellular and Molecular Life Sciences (2023)