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Open AccessFerumoxytol magnetic resonance angiography: a dose-finding study in patients with chronic kidney disease
Ferumoxytol is an alternative to gadolinium-based compounds as a vascular contrast agent for magnetic resonance angiography (MRA), particularly for patients with chronic kidney disease (CKD). However, dose-rel...
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Article
Open AccessFerumoxytol-enhanced magnetic resonance angiography for the assessment of potential kidney transplant recipients
Traditional contrast-enhanced methods for scanning blood vessels using magnetic resonance imaging (MRI) or CT carry potential risks for patients with advanced kidney disease. Ferumoxytol is a superparamagnetic...
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Article
Open AccessAblation of the androgen receptor from vascular smooth muscle cells demonstrates a role for testosterone in vascular calcification
Vascular calcification powerfully predicts mortality and morbidity from cardiovascular disease. Men have a greater risk of cardiovascular disease, compared to women of a similar age. These gender disparities s...
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Article
Open AccessIdentifying active vascular microcalcification by 18F-sodium fluoride positron emission tomography
Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is...
