31 Result(s)
within
Alessandro Larcher
Oncology
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Article
Biological characterization of renal masses using immuno-PET
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Article
Pulmonary lesion after surgery for renal cancer: progression or new primary?
To investigate clinical and radiological differences between kidney metastases to the lung (RCCM +) and metachronous lung cancer (LC) detected during follow-up in patients surgically treated for Renal Cell Car...
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Article
Long-term functional outcomes in patients undergoing radical nephrectomy for renal cell carcinoma and tumor thrombus
Up to 15% of patients with locally advanced renal cell carcinoma (RCC) harbors tumor thrombus (TT). In those cases, radical nephrectomy (RN) and thrombectomy represents the standard of care. We assessed the im...
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Article
Current practice and unmet training needs in robotic-assisted radical prostatectomy: investigation from the Junior ERUS/YAU working group
To access the current scenario of robotic-assisted radical prostatectomy training in multiple centers worldwide.
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Neglected lymph nodal metastases in patients with renal cancer: when to extend the anatomical template of lymph node dissection during nephrectomy
The role of lymph node dissection (LND) in patients with renal cell carcinoma (RCC) is still controversial. However, detecting lymph node invasion (LNI) is key due to prognostic implications and to identify pa...
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Article
Contemporary vs historical survival rates in metastatic clear cell renal carcinoma according to race/ethnicity
Systemic therapies (ST) improved contemporary survival rates, relative to historical in clear cell metastatic renal carcinoma (ccmRCC) patients. The magnitude of this improvement is unknown according to race/e...
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Article
How to optimize the use of adjuvant pembrolizumab in renal cell carcinoma: which patients benefit the most?
The KEYNOTE-564 trial showed improved disease-free survival (DFS) for patients with high-risk renal cell carcinoma (RCC) receiving adjuvant pembrolizumab as compared to placebo. However, if systematically admi...
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Article
Pancreatic metastases after surgery for renal cell carcinoma: survival and pathways of progression
Metastatic ccRCC has peculiar tropism in the pancreas. We describe the characteristics and pathways of progression of patients with PM in a large multi-institutional consortium and compare them to patients wit...
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Article
Retroperitoneal versus transepritoneal robot-assisted partial nephrectomy for postero-lateral renal masses: an international multicenter analysis
To assess the outcomes of retroperitoneal robot-assisted partial nephrectomy (r-RAPN) in a large cohort of patients with postero-lateral renal masses comparing to those of transperitoneal RAPN (t-RAPN).
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Article
Parenchymal biopsy in the management of patients with renal cancer
The role of non-tumour renal biopsy in predicting renal function after surgery for renal cell carcinoma (RCC) is poorly investigated. The aim of the study was to assess the impact of renal parenchymal histolog...
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Article
Renal cancer: overdiagnosis and overtreatment
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Article
Clinical, surgical, pathological and follow-up features of kidney cancer patients with Von Hippel-Lindau syndrome: novel insights from a large consortium
To investigate the natural history and follow-up after kidney tumor treatment of Von Hippel-Lindau (VHL) patients.
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Article
The impact of intraoperative bleeding on the risk of chronic kidney disease after nephron-sparing surgery
The current literature regarding the effect of blood loss (eBL) after nephron-sparing surgery (NSS) on long-term renal function is scarce. We tested the effect of eBL on the risk of develo** chronic kidney d...
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Article
The impact of sex and age on distribution of metastases in patients with renal cell carcinoma
Our objective was to investigate age and sex-related discrepancies on distribution of metastases in patients with metastatic renal cell carcinoma (RCC).
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Article
Neoadjuvant and adjuvant immunotherapy in renal cell carcinoma
The treatment landscape for renal cell carcinoma (RCC) is rapidly evolving. The aim of this review is to summarize the randomized-controlled trials evaluating the role of immunotherapy in neoadjuvant or adjuva...
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Article
Comparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma
To compare functional outcomes of partial nephrectomy (PN) and active surveillance (AS) in oncocytoma.
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Article
Prognostic factors in patients with small renal masses: a comparison between <2 vs. 2.1–4 cm renal cell carcinomas
Few data factually support the prognostic distinction between renal cell carcinomas (RCC) < 2 vs. 2.1–4 cm, in terms of cancer-specific mortality (CSM). We investigated CSM rates over time in <2 vs. 2.1–4 cm RCC,...
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Article
The role of 18F-FAZA PET/CT in detecting lymph node metastases in renal cell carcinoma patients: a prospective pilot trial
The accurate detection of nodal invasion is an unmet need in the clinical staging of renal cancer. Positron emission tomography (PET) with 18F-fluoroazomycin arabinoside (18F-FAZA), a hypoxia specific tracer, ...
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Article
Partial versus radical nephrectomy in very elderly patients: a propensity score analysis of surgical, functional and oncologic outcomes (RESURGE project)
To compare the outcomes of PN to those of RN in very elderly patients treated for clinically localized renal tumor.
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Article
Should partial nephrectomy be considered “elective” in patients with stage 2 chronic kidney disease? A comparative analysis of functional and survival outcomes after radical and partial nephrectomy
To compare renal function and survival outcomes in patients with baseline chronic kidney disease (CKD) stage 2 undergoing partial (PN) or radical nephrectomy (RN), as nephron-sparing surgery is considered to b...
