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Chapter
Data-Driven Approach Study for the Prediction and Detection of Infectious Disease Outbreak
In computational biology different methods including machine learning modeling, molecular docking, molecular dynamics simulations can provide depth knowledge for analyzing desired properties. In past few years...
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Article
Open AccessWater-organizing motif continuity is critical for potent ice nucleation protein activity
Bacterial ice nucleation proteins (INPs) can cause frost damage to plants by nucleating ice formation at high sub-zero temperatures. Modeling of Pseudomonas borealis INP by AlphaFold suggests that the central dom...
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Article
Spermidine, a caloric restriction mimetic, provides neuroprotection against normal and d-galactose-induced oxidative stress and apoptosis through activation of autophagy in male rats during aging
Spermidine (SPD) is a natural polyamine present in all living organisms and is involved in the maintenance of cellular homeostasis by inducing autophagy in different model organisms. Its role as a caloric rest...
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Chapter and Conference Paper
Prediction of Hydroxyurea Effect on Sickle Cell Anemia Patients Using Machine Learning Method
The objective of this paper is to predict the effect of hydroxyurea of individuals suffering from Sickle Cell Disease (SCD) using predictive machine learning techniques. Nowadays worldwide sickle cell disease ...
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Chapter and Conference Paper
Designing a Low-Cost Spin-Drying Desiccation Technique Using 3D Printed Whirligig Model for Preservation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells
In modern stem cell therapy, stem cells preservation is one of the major challenges. The present study aims to develop an advanced desiccation technique for the preservation of mesenchymal stem cells. Cryopres...
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Article
Novel Blowspun Nanobioactive Glass Doped Polycaprolactone/Silk Fibroin Composite Nanofibrous Scaffold with Enhanced Osteogenic Property for Bone Tissue Engineering
Blowspinning provides an efficient and easier way of nanofibers preparation that mimics the structure of native extracellular matrix (ECM) and can be applied as scaffolds to regenerate bone tissue at the defec...
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Article
A Review on 3D Printable Techniques for Tissue Engineering
A rapid revolution in the medical health care sector is expected due to the use of medical products fabricated from 3D printer technology. Several researches have been carried on the innovative achievements of...
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Chapter
Computational Methods for Develo** Novel Antiaging Interventions
Advances in computational methodologies have ushered in innovations in visualization, calculations, and prediction of factors relating to aging processes and concomitant diseases with novel strategies like com...
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Article
Autophagy Activation Alleviates Amyloid-β-Induced Oxidative Stress, Apoptosis and Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells
Autophagy is an evolutionary conserved catabolic process that ensures continuous removal of damaged cell organelles and long-lived protein aggregates to maintain cellular homeostasis. Although autophagy has be...
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Article
Stratifying Heterogeneous Dimension of Neurodegenerative Diseases: Intervention for Stipulating Epigenetic Factors to Combat Oxidative Stress in Human Brain
Neurodegenerative diseases affect the neurons of the human brain and decline the neural activities causing neurocognitive dysfunctions and brain and behavioral disorders. An intensive immunotherapy is used to ...
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Article
Open AccessEnhanced cryopreservation of MSCs in microfluidic bioreactor by regulated shear flow
Cell-matrix systems can be stored for longer period of time by means of cryopreservation. Cell-matrix and cell-cell interaction has been found to be critical in a number of basic biological processes. Tissue s...
