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  1. No Access

    Article

    Efficacy of redox nanoparticles for improving survival of transplanted cells in a mouse model of ischemic stroke

    The success of cell transplantation therapy for ischemic stroke is hindered by the low cell survival rate in poststroke brain, due in part to high free radical production and ensuing oxidative stress. We have ...

    Koji Hirata, Aiki Marushima, Yukio Nagasaki, Hiroshi Ishikawa… in Human Cell (2023)

  2. No Access

    Article

    Ventral Clival Branch of the Ascending Pharyngeal Artery as a Transosseous Feeder of an Arteriovenous Fistula Surrounding the Clival Lesions

    Arteriovenous fistulas (AVFs) adjacent to the clivus, such as cavernous sinus dural AVFs (CSDAVFs) and condylar AVFs, sometimes have an intraosseous shunted pouch and recruit blood supply from transosseous fee...

    Wataro Tsuruta, Tomokazu Sekine, Daiichiro Ishigami… in Clinical Neuroradiology (2023)

  3. No Access

    Article

    Development of cortical microvascularization in Moyamoya disease using the maximum intensity projection method from three-dimensional rotational angiography

    Neurosurgeons often experience increased cortical microvascularization in Moyamoya disease (MMD). However, there are no previous reports that radiologically evaluated preoperative cortical microvascularization...

    Yoshiro Ito, Hisayuki Hosoo, Aiki Marushima, Mikito Hayakawa… in Acta Neurochirurgica (2023)

  4. No Access

    Article

    Transplanted neural lineage cells derived from dental pulp stem cells promote peripheral nerve regeneration

    Cell therapy for peripheral nerve injury is a promising strategy as regenerative medicine that restores neurological function. However, challenges remain in producing suitable and sufficient amounts of autolog...

    Shohei Takaoka, Fumihiko Uchida, Hiroshi Ishikawa, Junko Toyomura… in Human Cell (2022)

  5. No Access

    Article

    Induced Neural Cells from Human Dental Pulp Ameliorate Functional Recovery in a Murine Model of Cerebral Infarction

    Human mesenchymal stem cells are a promising cell source for the treatment of stroke. Their primary mechanism of action occurs via neuroprotective effects by trophic factors, anti-inflammatory effects, and imm...

    Hideaki Matsumura, Aiki Marushima, Hiroshi Ishikawa… in Stem Cell Reviews and Reports (2022)

  6. Article

    Open Access

    Exercise training using hybrid assistive limb (HAL) lumbar type for locomotive syndrome: a pilot study

    With a rapidly aging population in Japan, locomotive syndrome is becoming an increasingly serious social problem. Exercise therapy using the lumbar type HAL, which is a wearable robot suit that can assist volu...

    Kousei Miura, Masao Koda, Kazuhiro Tamaki… in BMC Musculoskeletal Disorders (2021)

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  7. Article

    Open Access

    Levetiracetam versus fosphenytoin as a second-line treatment after diazepam for status epilepticus: study protocol for a multicenter non-inferiority designed randomized control trial

    Status epilepticus (SE) is an emergency condition for which rapid and secured cessation is important. Phenytoin and fosphenytoin, the prodrug of phenytoin with less severe adverse effects, have been recommende...

    Kensuke Nakamura, Aiki Marushima, Yuji Takahashi, Akio Kimura, Masahiro Asami… in Trials (2021)

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