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Article
Open AccessLung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis
Progressive lung fibrosis is associated with poorly understood aging-related endothelial cell dysfunction. To gain insight into endothelial cell alterations in lung fibrosis we performed single cell RNA-sequen...
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Article
Crystal ribcage: a platform for probing real-time lung function at cellular resolution
Understanding the dynamic pathogenesis and treatment response in pulmonary diseases requires probing the lung at cellular resolution in real time. Despite advances in intravital imaging, optical imaging of the...
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Article
Tackling neurodegenerative diseases: animal models of Alzheimer’s disease and Parkinson’s disease
Our ageing society is confronted with a dramatic increase in incidence of age-related neurodegenerative diseases; biomedical research leading to novel therapeutic strategies is crucial to address this problem....