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  1. Article

    Open Access

    Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature

    To validate the expression of a urine-based bladder cancer associated diagnostic signature comprised of 10 targets; ANG, CA9, MMP9, MMP10, SERPINA1, APOE, SDC1, VEGFA, SERPINE1 and IL8 in bladder tumor tissues.

    Ge Zhang, Evan Gomes-Giacoia, Yunfeng Dai, Adrienne Lawton in Diagnostic Pathology (2014)

  2. Article

    Open Access

    Matrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors

    Cancer invasion and metastasis develops through a series of steps that involve the loss of cell to cell and cell to matrix adhesion, degradation of extracellular matrix and induction of angiogenesis. Different...

    Ge Zhang, Makito Miyake, Adrienne Lawton, Steve Goodison, Charles J Rosser in BMC Cancer (2014)

  3. Article

    Open Access

    Clinical implications in the shift of syndecan-1 expression from the cell membrane to the cytoplasm in bladder cancer

    To determine the diagnostic and prognostic capability of urinary and tumoral syndecan-1 (SDC-1) levels in patients with cancer of the urinary bladder.

    Makito Miyake, Adrienne Lawton, Yunfeng Dai, Myron Chang, Lourdes Mengual in BMC Cancer (2014)

  4. Article

    Open Access

    Investigation of CCL18 and A1AT as potential urinary biomarkers for bladder cancer detection

    In this study, we further investigated the association of two biomarkers, CCL18 and A1AT, with bladder cancer (BCa) and evaluated the influence of potentially confounding factors in an experimental model.

    Makito Miyake, Shanti Ross, Adrienne Lawton, Myron Chang, Yunfeng Dai in BMC Urology (2013)

  5. Article

    Open Access

    Erythropoietin is a JAK2 and ERK1/2 effector that can promote renal tumor cell proliferation under hypoxic conditions

    Erythropoietin (EPO) provides an alternative to transfusion for increasing red blood cell mass and treating anemia in cancer patients. However, recent studies have reported increased adverse events and/or redu...

    Makito Miyake, Steve Goodison, Adrienne Lawton in Journal of Hematology & Oncology (2013)

  6. Article

    Open Access

    Chemokine (C-X-C) ligand 1 (CXCL1) protein expression is increased in aggressive bladder cancers

    Chemokines, including chemokine (C-X-C motif) ligand 1 (CXCL1), may regulate tumor epithelial-stromal interactions that facilitate tumor growth and invasion. Studies have linked CXCL1 expression to gastric, co...

    Makito Miyake, Adrienne Lawton, Steve Goodison, Virginia Urquidi in BMC Cancer (2013)

  7. Article

    Open Access

    Pheochromocytoma of the urinary bladder: a systematic review of the contemporary literature

    Pheochromocytoma (paraganglioma) of the urinary bladder is a rare tumor. Herein we sought to review the contemporary literature on pheochromocytomas of the urinary bladder in order to further illustrate the pr...

    Jonathan A Beilan, Adrienne Lawton, Julio Hajdenberg, Charles J Rosser in BMC Urology (2013)

  8. Article

    Open Access

    Locally advanced paraganglioma of the urinary bladder: a case report

    Paraganglioma of the urinary bladder is a rare tumor. Herein we sought to describe a case of locally advanced paraganglioma of the urinary bladder managed by partial cystectomy and extended pelvic lymph node d...

    Jonathan Beilan, Adrienne Lawton, Julio Hajdenberg, Charles J Rosser in BMC Research Notes (2013)