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Article
Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing
Multiple myeloma (MM) is a neoplastic plasma-cell disorder characterized by clonal proliferation of malignant plasma cells. Despite extensive research, disease heterogeneity within and between treatment-resist...
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Article
Open AccessCystatin C takes part in melanoma-microglia cross-talk: possible implications for brain metastasis
The development of melanoma brain metastasis is largely dependent on mutual interactions between the melanoma cells and cells in the brain microenvironment. Here, we report that the extracellular cysteine prot...
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Article
The six Tomato yellow leaf curl virus genes expressed individually in tomato induce different levels of plant stress response attenuation
Tomato yellow leaf curl virus (TYLCV) is a begomovirus infecting tomato plants worldwide. TYLCV needs a healthy host environment to ensure a successful infection cycle for long periods. H...
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Article
Open AccessCorrection: Corrigendum: Tomato yellow leaf curl virus infection mitigates the heat stress response of plants grown at high temperatures
Scientific Reports 6: Article number: 19715; Published online: 21 January 2016; Updated: 11 May 2016 The original version of this Article contained errors in the spelling of the authors Ghandi Anfoka, Adi Mosh...
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Article
Open AccessTomato yellow leaf curl virus infection mitigates the heat stress response of plants grown at high temperatures
Cultured tomatoes are often exposed to a combination of extreme heat and infection with Tomato yellow leaf curl virus (TYLCV). This stress combination leads to intense disease symptoms and yield losses. The respo...
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Article
Open AccessThe Tomato yellow leaf curl virus V2 protein forms aggregates depending on the cytoskeleton integrity and binds viral genomic DNA
The spread of Tomato yellow leaf curl virus (TYLCV) was accompanied by the formation of coat protein (CP) aggregates of increasing size in the cytoplasm and nucleus of infected tomato (Solanum lycopersicum) cells...
