5 Result(s)
within
Achim Berthele
Neurobiology
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Article
Open AccessCerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients
Comprehensive data on the cerebrospinal fluid (CSF) profile in patients with COVID-19 and neurological involvement from large-scale multicenter studies are missing so far.
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Article
Open AccessCytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases
Cytokines play multiple roles during neuro-inflammatory processes and several cytokines have been studied in the context of specific diseases. This study provides a comprehensive picture of cerebrospinal fluid...
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Article
Open AccessCXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation
The chemokines and cytokines CXCL13, CXCL12, CCL19, CCL21, BAFF and APRIL are believed to play a role in the recruitment of B cells to the central nervous system (CNS) compartment during neuroinflammation. To ...
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Article
Open AccessContrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
The diagnostic and pathophysiological relevance of antibodies to aquaporin-4 (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been intensively studied. However, little is known so...
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Article
Open AccessAnti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders
Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmun...
