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Article
Open AccessThe potential of adipokines in identifying multiple trauma patients at risk of develo** multiple organ dysfunction syndrome
Multiple organ dysfunction syndrome (MODS) and the consecutive multiple organ failure (MOF) are severe and dreaded complications with a high mortality in multiple trauma patients. The aim of this study was to ...
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Article
Open AccessDirect comparison of 3D and 2D cultivation reveals higher osteogenic capacity of elderly osteoblasts in 3D
The aim of this study was the investigation of the osteogenic potential of human osteoblasts of advanced donor age in 2D and 3D culture.
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Article
Open AccessAuthor Correction: Effect of donor age and 3D-cultivation on osteogenic differentiation capacity of adipose-derived mesenchymal stem cells
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessEffect of donor age and 3D-cultivation on osteogenic differentiation capacity of adipose-derived mesenchymal stem cells
Background and Purpose: Age and co-morbidities compromise healing tendencies of traumatic fractures in geriatric patients. Non-healing fractures may need regenerative medicine techniques involving autologous mese...
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Article
Open AccessCytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases
Cytokines play multiple roles during neuro-inflammatory processes and several cytokines have been studied in the context of specific diseases. This study provides a comprehensive picture of cerebrospinal fluid...
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Article
Open AccessAdipose-derived mesenchymal stem cells from liposuction and resected fat are feasible sources for regenerative medicine
The use of mesenchymal stem cells (MSCs) in research and in regenerative medicine has progressed. Bone marrow as a source has drawbacks because of subsequent morbidities. An easily accessible and valuable sour...
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Article
Platelets modulate the immune response following trauma by interaction with CD4+ T regulatory cells in a mouse model
CD4+ T regulatory cells (Tregs) play a pivotal role in the anti-inflammatory immune response following trauma. The mechanisms of CD4+ Treg activation are mostly unknown. Here, we hypothesize that platelets reg...
