7 Result(s)
within
Achim Berthele
Biomedicine
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Article
Open AccessCerebrospinal fluid lactate levels along the Alzheimer’s disease continuum and associations with blood-brain barrier integrity, age, cognition, and biomarkers
Cerebrospinal fluid (CSF) lactate levels have been suggested to be associated with disease severity and progression in several neurological diseases as an indicator of impaired energy metabolism, neuronal deat...
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Article
Open AccessCerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients
Comprehensive data on the cerebrospinal fluid (CSF) profile in patients with COVID-19 and neurological involvement from large-scale multicenter studies are missing so far.
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Article
Open AccessCytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases
Cytokines play multiple roles during neuro-inflammatory processes and several cytokines have been studied in the context of specific diseases. This study provides a comprehensive picture of cerebrospinal fluid...
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Article
Visual imagery and functional connectivity in blindness: a single-case study
We present a case report on visual brain plasticity after total blindness acquired in adulthood. SH lost her sight when she was 27. Despite having been totally blind for 43 years, she reported to strongly rely...
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Article
Open AccessCXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation
The chemokines and cytokines CXCL13, CXCL12, CCL19, CCL21, BAFF and APRIL are believed to play a role in the recruitment of B cells to the central nervous system (CNS) compartment during neuroinflammation. To ...
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Article
Open AccessContrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
The diagnostic and pathophysiological relevance of antibodies to aquaporin-4 (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been intensively studied. However, little is known so...
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Article
Open AccessAnti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders
Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmun...
