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Article
Open AccessSymptom burden, psychosocial distress and palliative care needs in heart failure – A cross-sectional explorative pilot study
Beyond guideline-directed treatments aimed at improving cardiac function and prognosis in heart failure (HF), patient-reported outcomes have gained attention.
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Article
Open AccessNational strategy for palliative care of severely ill and dying people and their relatives in pandemics (PallPan) in Germany - study protocol of a mixed-methods project
In the SARS-CoV-2 pandemic, general and specialist Palliative Care (PC) plays an essential role in health care, contributing to symptom control, psycho-social support, and providing support in complex decision...
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Article
Open AccessA pre-registered short-term forecasting study of COVID-19 in Germany and Poland during the second wave
Disease modelling has had considerable policy impact during the ongoing COVID-19 pandemic, and it is increasingly acknowledged that combining multiple models can improve the reliability of outputs. Here we rep...
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Article
Observation of an fcc–Co nanolayer grown between CoO and amorphous Si
The thermodynamically crystallographic phase of Co at ambient conditions is hexagonal-close-packed. However, it has been found that given a crystallographic support from a suitable substrate, the high-temperat...
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Article
Open AccessNovel members of quinoline compound family enhance insulin secretion in RIN-5AH beta cells and in rat pancreatic islet microtissue
According to clinical data, some tyrosine kinase inhibitors (TKIs) possess antidiabetic effects. Several proposed mechanisms were assigned to them, however their mode of action is not clear. Our hypothesis was...
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Article
Recovery of Zn from wastewater of zinc plating industry by precipitation of doped ZnO nanoparticles
In this study, a facile precipitation process to treat wastewater from zinc plating industry is presented. Water purification rates of Zn range between 96.40 % and 99.99 % depending on the reaction conditions....
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Chapter
Cobalt/Cobaltoxide Exchange Bias System for Diluted Ferromagnetic Alloy Films in Superconducting Spin-Valves
The present work reports on the influence of a Cobalt sublayer on a conventional exchange bias CoOx/Cu41Ni59 interface. For superconducting spintronics the ability to exchange bias diluted ferromagnetic alloys is...
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Article
LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention
The extracellular matrix protein lectin galactoside-binding soluble 3 binding protein (LGALS3BP) constitutes a negative prognostic marker of cancer onset and progression with increasing value in clinical appli...
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Article
HGF induces novel EGFR functions involved in resistance formation to tyrosine kinase inhibitors
The epidermal growth factor receptor (EGFR) is overexpressed and activated in many human cancers and predicts poor patient prognosis. Targeting the kinase domain with specific EGFR tyrosine kinase inhibitors (...
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Article
The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells
Mutational analysis of oncogenes is critical for our understanding of cancer development. Oncogenome screening has identified a fibroblast growth factor receptor 4 (FGFR4) Y367C mutation in the human breast cance...
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Article
Overexpression of Csk-binding protein contributes to renal cell carcinogenesis
C-terminal Src kinase (Csk)-binding protein (Cbp) is a transmembrane adaptor protein that localizes exclusively in lipid rafts, where it regulates Src family kinase (SFK) activities through recruitment of Csk....
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Article
Blind und sehend in einer Person
Es wird der Fall einer Patientin mit dissoziativer Identitätsstörung vorgestellt, die nach 15-jähriger, als kortikal diagnostizierter Blindheit im Laufe einer psychotherapeutischen Behandlung schrittweise wied...
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Article
Applicability of single photon detection for laser radar
We give a brief overview on the implementation of single photon detection for laser radar applications, with a special focus on laser scanners. The current state of the art of single photon detection modules a...
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Article
Csk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activation
Epidermal growth factor receptor (EGFR) and Src tyrosine kinase cooperate in regulating EGFR-mediated cell signaling and promoting cell transformation and tumorigenesis in pathological conditions. Activation o...
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Article
Erratum: Mig6 is a negative regulator of EGF receptor–mediated skin morphogenesis and tumor formation
Nat. Med. 12, 568–573 (2006); published online 30 April 2006; corrected after print 16 June 2006 In the version of this article initially published, Errfi1 was incorrectly referred to as Erffi1 in several inst...
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Article
Open AccessFGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients
A single nucleotide polymorphism in the gene for FGFR4 (−Arg388) has been associated with progression in various types of human cancer. Although fibroblast growth factors (FGFs) belong to the most important gr...
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Article
Abundance, diversity, and vitality of mycorrhizae of Scots pine (Pinus sylvestris L.) in lignite recultivation sites
Scots pine (Pinus sylvestris L.) stands cover large areas in the Lusatian and the Middle German lignite mining districts. Due to adverse chemical substrate conditions, the root systems of the trees are restricted...
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Article
Evolution of Coherent Interphase Boundaries during Annealing of Multilayers: A Monte Carlo Study
Some properties of nanoscale multilayers, as for example the giant magnetoresistance, are expected to depend sensitively on the structure of the interphase boundaries. Recent experimental work aimed to elucida...
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Article
The cDNA Microarray Profiling of Protein Kinases and Phosphatases: Molecular Portrait of Human Prostate Carcinomas
Hybridization with cDNA arrays was used to obtain expression profiles of 263 protein-tyrosine kinase (PTK), protein-tyrosine phosphatase (PTP), dual-specific phosphatase (DuSP), and other genes for the normal ...
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Article
Molecular Portrait of Human Kidney Carcinomas: The cDNA Microarray Profiling of Kinases and Phosphatases Involved in the Cell Signaling Control
Hybridization with cDNA arrays was used to obtain expression profiles of 214 protein-tyrosine kinase, protein-tyrosine phosphatase, dual specificity phosphatase, and other genes for kidney carcinomas (KC) and ...
