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Article
AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-β-mediated ERK signaling
Epithelial-to-mesenchymal transdifferentiation (EMT) mediated by transforming growth factor-β (TGF-β) signaling leads to aggressive cancer progression. In this study, we identified zinc-α2-glycoprotein (AZGP1,...
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Article
The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells
Mutational analysis of oncogenes is critical for our understanding of cancer development. Oncogenome screening has identified a fibroblast growth factor receptor 4 (FGFR4) Y367C mutation in the human breast cance...
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Article
Open AccessFGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients
A single nucleotide polymorphism in the gene for FGFR4 (−Arg388) has been associated with progression in various types of human cancer. Although fibroblast growth factors (FGFs) belong to the most important gr...
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Article
Die Bestimmung von Uran und Plutonium im Rahmen der Ausscheidungsanalyse
Eine in der Praxis angewandte Analysenmethode zur Bestimmung von Plutonium in Harnproben wurde mit Hilfe von Tracerversuchen mit236Pu,233U und241Am hinsichtlich ihrer radiochemischen Ausbeute und ihrer Trenneffiz...