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Article
Open AccessUse of drug-induced sleep endoscopy in Germany—an analysis based on claims data
Drug-induced sleep endoscopy (DISE) has recently gained relevance as a diagnostic tool for obstructive sleep apnea (OSA). However, it is unclear to what extent and in which patient cohorts DISE is used in Germ...
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Article
Open AccessDiagnosis and treatment of isolated snoring—open questions and areas for future research
Snoring is a common phenomenon which is generated by vibration of soft tissue of the upper airway during sleep. Due to the high incidence of isolated snoring and the substantial burden for the patient and the ...
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Article
Complete concentric collapse at the soft palate in sleep endoscopy: what change is possible after UPPP in patients with CPAP failure?
The aim of this work was to assess whether uvulopalatopharyngoplasty in patients with failure for positive airway pressure not only reduces the degree of obstructive sleep apnea but also to determine as well i...
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Article
Open AccessTrends and regional variations in the administrative prevalence of attention-deficit/hyperactivity disorder among children and adolescents in Germany
There is a controversy regarding temporal trends in prevalence of attention-deficit/hyperactivity disorder (ADHD). Using nationwide claims data containing data for approximately six million statutory health in...
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Article
Patient-reported outcome: results of the multicenter German post-market study
Upper airway stimulation (UAS) is an alternative second-line treatment option for patients with obstructive sleep apnea (OSA). In our substudy of a previous multicentre study of patients implanted with UAS, we...
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Article
Hypoglossusnervstimulation bei obstruktiver Schlafapnoe
Der Goldstandard in der Behandlung der obstruktiven Schlafapnoe (OSA) ist die nächtliche kontinuierliche Positivdruckbeatmung, die „continuous positive airway pressure“ (CPAP). Ein gewisser Anteil der Patiente...
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Article
ENT-specific therapy of obstructive sleep apnoea in adults
The German Society of Otorhinolaryngology, Head and Neck Surgery recently has released the abbreviated version of its scientific guideline “ENT-specific therapy of obstructive sleep apnoea (OSA) in adults”, wh...
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Article
Open AccessAssociations of anthropometric markers with serum metabolites using a targeted metabolomics approach: results of the EPIC-potsdam study
The metabolic consequences of type of body shape need further exploration. Whereas accumulation of body mass in the abdominal area is a well-established metabolic risk factor, accumulation in the gluteofemoral...
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Article
Functional outcome of tongue motions with selective hypoglossal nerve stimulation in patients with obstructive sleep apnea
Selective upper airway stimulation of the hypoglossal nerve is a novel therapy option for obstructive sleep apnea. Different tongue motions were observed after surgery during active therapy.
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Article
Leitlinie: „HNO-spezifische Therapie der obstruktiven Schlafapnoe bei Erwachsenen“ Kurzfassung
Die hier vorgelegte S2e-Leitlinie ist die Aktualisierung der Vorgängerleitlinie „Therapie der obstruktiven Schlafapnoe des Erwachsenen“. Die Aktualisierung erfolgte im Auftrag der Deutschen Gesellschaft für Ha...
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Article
Open AccessAn epidemiologic risk prediction model for ovarian cancer in Europe: the EPIC study
Ovarian cancer has a high case-fatality ratio, largely due to late diagnosis. Epidemiologic risk prediction models could help identify women at increased risk who may benefit from targeted prevention measures,...
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Lungenmetastasen bei Karzinomen des Kopf-Hals-Bereiches
Bösartige Tumorerkrankungen des Kopf-Hals-Bereiches stehen weltweit mit einer Prävalenz von 6 % an 6. Stelle aller Neoplasien und damit im besonderen Focus. Bei Männern erreichen diese Karzinome mit 7,9 % die ...
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Article
A glycine-rich RNA-binding protein affects gibberellin biosynthesis in Arabidopsis
The RNA-binding protein Arabidopsis thaliana glycine-rich RNA-binding protein 7 (AtGRP7) regulates the steady-state abundance of numerous target transcripts in A. thaliana. Here we show that the GA1 and GA2 trans...
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Article
S2k-Leitlinie „Diagnostik und Therapie des Schnarchens des Erwachsenen“
Ziel dieser Leitlinie ist die Förderung einer qualitativ hochwertigen ärztlichen Versorgung von Erwachsenen mit Schnarchen. Die Leitlinie wurde für die Anwendung im Rahmen der ambulanten und stationären Versor...
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Article
Effects of immunosuppression on alpha and beta cell renewal in transplanted mouse islets
Immunosuppressive drugs used in human islet transplantation interfere with the balance between beta cell renewal and death, and thus may contribute to progressive graft dysfunction. We analysed the influence o...
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Article
Erratum to: Body iron stores and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study
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Open AccessBody iron stores and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study
The aim of this study was to prospectively examine the association between body iron stores and risk of type 2 diabetes.
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Article
Reliability of fasting plasma alkylresorcinol metabolites concentrations measured 4 months apart
Alkylresorcinols (AR) have been suggested as specific dietary biomarkers of whole-grain wheat and rye intake. AR are metabolised to 3,5-dihydroxybenzoic acid (DHBA) and 3-(3,5-dihydroxyphenyl)-1-propanoic acid...
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Article
The association of education with long-term weight change in the EPIC-PANACEA cohort
Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examin...
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The association of lifetime alcohol use with measures of abdominal and general adiposity in a large-scale European cohort
The relation between lifetime use of alcohol and measures of abdominal and general adiposity is unknown.
