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  1. Article

    Isolation of two H1N2 influenza viruses from swine in France

    Samples collected in 1987 and 1988 in Brittany from influenzainfected swine made it possible to isolate and antigenically characterize two H1N2 recombinant viruses (Sw/France/5027/87 and Sw/France/5550/88). Th...

    J. M. Gourreau, C. Kaiser, M. Valette, A. R. Douglas, J. Labie in Archives of Virology (1994)

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    Article

    Antigenic and genetic characterization of current influenza strains

    Annually the influenza centre receives more than 1000 virus isolates from around the world to monitor the changing pattern of viruses causing influenza throughout the year. These are characterized antigenicall...

    A. J. Hay, A. R. Douglas, D. B. Sparrow, K. R. Cameron in European Journal of Epidemiology (1994)

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    Article

    Influenza A virus enhances IgE-mediated histamine release from human basophil leukocytes. Examination of the effect of viral neuraminidase and haemagglutinin

    Histamine release caused by anti-IgE was examined in leukocyte suspensions from 10 healthy individuals. Influenza A virus was found to enhance the histamine release but did not release histamineper se. When monoc...

    P. Clementsen, A. R. Douglas, J. J. Skehel, C. Hannoun in Agents and Actions (1989)

  4. Article

    Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin

    Antigenic variation in the haemagglutinin (HA) glycoprotein of influenza virus is associated with recurrent epidemics of respiratory disease in man (for review see ref. 1). We have examined the size of structu...

    M. Knossow, R. S. Daniels, A. R. Douglas, J. J. Skehel, D. C. Wiley in Nature (1984)

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    Chapter

    Studies on the Structure and Activities of Influenza Virus Haemagglutinin

    The initial events in infection by influenza virus involve binding of virus to sialic acid residues of glycosylated membrane receptors, endocytosis, and fusion of the membranes of virus and endosome. Virus ads...

    J. J. Skehel, R. S. Daniels, A. R. Douglas, M. Knossow in Mechanisms of Viral Pathogenesis (1984)