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Changes in body weight and pulse: outcome events in overweight and obese subjects with cardiovascular disease in the SCOUT trial
The Sibutramine Cardiovascular OUTcomes (SCOUT) trial showed a significantly increased relative risk of nonfatal cardiovascular events, but not mortality, in overweight and obese subjects receiving long-term s...
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Article
Changes in body weight and blood pressure: paradoxical outcome events in overweight and obese subjects with cardiovascular disease
The Sibutramine Cardiovascular OUTcomes (SCOUT) trial showed a significantly increased relative risk of nonfatal cardiovascular events, but not mortality, in overweight and obese subjects receiving long-term s...
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Article
Association of anemia with the risk of cardiovascular adverse events in overweight/obese patients
Anemia is associated with increased cardiovascular risks. Obesity may cause anemia in several ways, for example, by low-grade inflammation and relative iron deficit. The outcomes associated with anemia in over...
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Article
Effective weight management practice: a review of the lifestyle intervention evidence
Despite the existence of guidelines for obesity management, uncertainty remains as to what interventions comprise effective practice. This uncertainty could act as a barrier to busy health care professionals, ...
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Article
Association between obesity and health-related quality of life in patients with coronary artery disease
In patients with coronary artery disease (CAD), obesity is paradoxically associated with better survival (the ‘obesity paradox’). Our objective was to determine whether this counterintuitive relationship exten...
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Article
A proposed clinical staging system for obesity
Current classifications of obesity based on body mass index, waist circumference and other anthropometric measures, although useful for population studies, have important limitations when applied to individual...
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Article
Salt-sensitive men show reduced heart rate variability, lower norepinephrine and enhanced cortisol during mental stress
Salt sensitivity (SS) represents a risk factor for essential hypertension, which has been related to enhanced cardiovascular stress reactivity possibly mediated by increased noradrenergic susceptibility. We in...
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The Third International Symposium on Obesity and Hypertension ISOH'03: ‘Genetics and Molecular Mechanisms’ (October 23–25, 2003, Berlin Germany)
The Third International Symposium on Obesity and Hypertension (ISOH'03) was held on 23–25, October 2003 at the Max Delbruck Center for Molecular Medicine in Berlin-Buch, Germany. The meeting, which consisted l...
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Article
Influence of Sibutramine on blood pressure: evidence from placebo-controlled trials
Sibutramine, a serotonin and norepinephrine transporter inhibitor, is widely used as an adjunctive obesity treatment. There have been concerns that norepinephrine reuptake inhibition with sibutramine could exa...
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Article
Recognition and management of overweight and obesity in primary care in Germany
BACKGROUND: In contrast to the well-documented high prevalence of overweight and obesity in the general population, the prevalence, recognition rates and management by primary care physicians—as the core gatekeep...
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Article
Moxonidine in the treatment of overweight and obese patients with the metabolic syndrome: a postmarketing surveillance study
Moxonidine is a centrally active imidazoline receptor agonist that effectively lowers blood pressure and has been shown to have beneficial effects on lipid and carbohydrate metabolism. We assessed the efficacy...
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Epidemiologische, genetische und therapeutische Aspekte der Adipositas