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Article
An Electrostatic Lens for Correcting the Ion Beam of a Magnetron Source
The schematic diagram and design of an electrostatic lens for correction and additional focusing of a beam coming out of a magnetron-type ion source are described. A drawing of such a lens is presented.
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Article
Synthesis, Structure, and Properties of the Iron Nitrosyl Complex with 2-Ethyl-4-pyridinecarbothioamide
The synthesis and data on the physicochemical characteristics and biological activity of the new iron nitrosyl complex (Q+)2[Fe2(S2O3)2(NO)4]2– (I), where Q+ is protonated 2-ethyl-4-pyridinecarbothioamide (C8H11N
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Article
Effect of F Substituents in Thiophenol on the Structure and Properties of µ2-S-(Difluorothiolate)tetranitrosyl Iron Binuclear Complexes
Two new neutral binuclear tetranitrosyl iron complexes of general formula [Fe2R2(NO)4] with R = 2,4-difluorothiophenyl (complex 1) and 3,4-difluorothiophenyl (complex 2), donors of nitrogen monoxide (NO), were pr...
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Article
Structure and biological activity of 2-ethyl-3-hydroxy-6-methylpyridinium nitroxysuccinate
The structure of 2-ethyl-3-hydroxy-6-methylpyridinium nitroxysuccinate (2) was studied. The cytotoxicity of this compound and its ability to have an effect on the level of intracellular nitrogen monoxide, as well...
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Article
Pyridine Derivative of Succinic Acid Hydroxylamide Enhances the Cytotoxic Effect of Cisplatin and Actinomycin D
We studied the possibility of inhibition of histone deacetylases (HDAC) in the nuclear extract of HeLa cells by N1-hydroxy-N4-(pyridin-4-yl)succinamide (compound 1). Compound 1 inhibits HDAC and showed low tox...
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Article
Refined Results of Measurements of the Lifetime of Unstable Ions \({\text{D}}_{2}^{ - }\) and HD–
The results of measuring the lifetime of negative molecular ions \({\text{D}}_{2}^{ - }\) and HD─ were refined by r...
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Article
Electrolytic-Plasma Jet Polishing of Additively Manufactured Gas Turbine Engine Components
The study of electrolytic-plasma jet polishing process was made using a high-speed camera. The process visualization allowed us to find optimization methods. Electrolytic-plasma jet polishing capabilities are ...
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Article
Peculiarities of Using Potassium Ferricyanide as the Mediator for Bioanodes Based on Escherichia coli
The performance of a bioanode based on living cells Escherichia coli in the electrochemical oxidation of glucose is studied. It is shown that potassium ferricyanide can serve as the mediator in this bioelectrocat...
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Article
New Amphiphilic Branched Copolymers of N-Vinylpyrrolidone with Methacrylic Acid for Biomedical Applications
Amphiphilic copolymers of N-vinylpyrrolidone and methacrylic acid, and triethylene glycol dimethacrylate (branching agent) are synthesized by radical copolymerization in toluene and ethanol; their main physicoche...
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Article
Laser Powder Surfacing of Gas-Turbine Components and Restoration of the Metal Powder
Laser machining has been used for some time in producing aircraft engines, in Russia and elsewhere. The introduction of new industrial processes entails extensive testing and research, and so years may pass be...
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Article
Numerical Simulation of Convective Heat Transfer under Forced Motion of Heat Carrier in Cooling Systems with Split Fin
The paper is devoted to numerical simulation of heat transfer enhancement processes in forced convective cooling systems based on split fins. The choice of the k–ω-SST turbulence model is substantiated, the numer...
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Article
Nrf2-Dependent Expression of Glutathione Antioxidant System Genes and Redox Status in Cells of In Vivo Drug-Resistant Murine P388 Leukemia Strains
We measured the content of ROS and malondialdehyde in cells of in vivo drug-resistant murine P388 leukemia strains. It was found that the strains did not differ by malondialdehyde concentration, but intracellular...
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Article
Influence of Tumor Suppressor p53 Functioning on the Expression of Antioxidant System Genes under the Action of Cytotoxic Compounds
The effect of inhibition of the tumor suppressor p53 on the antioxidant system genes expression under the influence of cytotoxic compounds of the platinum group was studied. It was found that the action of pla...
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Article
Electrochemical Peculiarities of Mediator-Assisted Bioelectrocatalytic Oxidation of Glucose by a New Type of Bioelectrocatalyst
A protein extract of microbe cells is studied as a bioelectrocatalyst for glucose oxidation. The microbial protein extract prepared from Escherichia coli BB, which comprises all enzymes of the life cycle of these...
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Article
Polymer nanoparticles of N-vinylpyrrolidone loaded with an organic aminonitroxyl platinum (iv) complex. Characterization and investigation of their in vitro cytotoxicity
The conditions for obtaining stable aqueous solutions of a lipophilic aminonitroxyl platinum complex, namely, e-amine-d-(4-amino-2,2,6,6-tetramethylpiperidine 1-oxyl)-a, f-bis(octanoato)-b, c-dichloroplatinum(iv)...
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Article
Activity of Antioxidant Enzymes and Content of Reduced Glutathione in Cells of Drug-Resistant Murine Leukemia P388 Strains
Activities of superoxide dismutase and catalase and content of reduced glutathione in cells of drug-resistant murine leukemia P388 strains were studied without or after administration of antitumor compounds. I...
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Article
Antibacterial activity of [1Fe-2S]- and [2Fe-2S]-nitrosyl complexes as nitric oxide donors
The biological activity of a series of sulfur-nitrosyl iron complexes (NICs) depends on the structure of the ligands and the position of the functional groups in the aromatic ring of the ligand. Differences in...
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Article
Effect of Chitosan-(Poly)Nitroxides on Normal and Tumor Cells under Conditions of Induced Oxidative Stress
The cytotoxicity and antioxidant effects of chitosan-(poly)nitoxides of different molecular weights containing a nitroxide radical of the piperidine structure were studied on tumor (HeLa, A172, and HepG2) and ...
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Article
Antioxidant properties of chitosan-(poly)nitroxides under induced oxidative stress
The cytotoxicity and antioxidant properties of water-soluble (at physiological pH) chitosan- (poly)nitroxides (CPNs) containing pyrroline-based nitroxide and having different molecular weights of the polysacch...
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Article
A Method for Measuring the Lifetimes of Unstable Ions
A method for measuring the lifetimes of unstable ions using an electrostatic analyzer with the spatial focusing and rotation angles of 360° and 720° is described. A drawing of this analyzer is presented.