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Article
Open AccessOccupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study
Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma.
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Article
Open AccessTest–retest reliability of an infectious disease questionnaire and evaluation of self-assessed vulnerability to infections
Large scale population-based studies focusing on infectious diseases are scarce. This may be explained by methodological obstacles concerning ascertainment of data on infectious diseases requiring, e.g. collec...
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Article
Feasibility and quality development of biomaterials in the pretest studies of the German National Cohort
The German National Cohort (GNC) is designed to address research questions concerning a wide range of possible causes of major chronic diseases (e.g. cancer, diabetes, infectious, allergic, neurologic and card...
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Article
A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus
Recent genome-wide association studies (GWAS) of Hodgkin lymphoma (HL) have identified associations with genetic variation at both HLA and non-HLA loci; however, much of heritable HL susceptibility remains une...
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Article
Open AccessInflammation marker and risk of pancreatic cancer: a nested case–control study within the EPIC cohort
Established risk factors for pancreatic cancer include smoking, long-standing diabetes, high body fatness, and chronic pancreatitis, all of which can be characterised by aspects of inflammatory processes. Howe...
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Article
Diabetes mellitus, glycated haemoglobin and C-peptide levels in relation to pancreatic cancer risk: a study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
There has been long-standing debate about whether diabetes is a causal risk factor for pancreatic cancer or a consequence of tumour development. Prospective epidemiological studies have shown variable relation...
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Article
Open AccessAntibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case–control study
Kaposi's sarcoma-associated herpes virus is associated with primary effusion lymphoma and multicentric Castleman's disease.
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Article
Diet and hip fractures among elderly Europeans in the EPIC cohort
Evidence on the role of diet during adulthood and beyond on fracture occurrence is limited. We investigated diet and hip fracture incidence in a population of elderly Europeans, participants in the European Pr...
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Article
Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk
Interactions between environment and immune system play an essential role in the aetiology of immunopathologies, including lymphomas. Toll-like receptors (TLR) belong to a group of pattern recognition receptor...
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Article
Open AccessTobacco smoking, alcohol drinking and Hodgkin's lymphoma: a European multi-centre case–control study (EPILYMPH)
We analysed the effects of tobacco and alcohol in the aetiology of Hodgkin's lymphoma (HL), based on 340 cases and 2465 controls enrolled in Spain, France, Italy, Germany, Ireland and Czech Republic, between 1...
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Article
Open AccessCytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)
Atopy and allergic phenotypes are biologically characterized by an imbalanced T helper cell response skewed towards a type 2 (TH2) immune response associated with elevated serum immunoglobulin E (IgE) levels. ...
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Article
Allergic sensitisation and allergic rhinitis are associated with n-3 polyunsaturated fatty acids in the diet and in red blood cell membranes
Due to inconsistent results based on dietary intake data, unsaturated fatty acids in red blood cell (RBC) membranes and diet were used to investigate their association with allergic sensitisation and allergic ...
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Article
Tumorepidemiologie
Das Educational “Tumorepidemiologie” hatte zum Ziel, Einblicke in gegenwärtig besonders intensiv bearbeitete bzw. diskutierte Bereiche der Epidemiologie zu geben. Einer der Beiträge gab einen Überblick über di...