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Article
Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis
The host genetic basis of mixed cryoglobulin vasculitis is not well understood and has not been studied in large cohorts. A genome-wide association study was conducted among 356 hepatitis C virus (HCV) RNA-pos...
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Article
Open AccessNuclear NHERF1 expression as a prognostic marker in breast cancer
Our purpose was to investigate whether Na+/H+ exchanger regulatory factor 1 (NHERF1) expression could be linked to prognosis in invasive breast carcinomas. NHERF1, an ezrin-radixin-moesin (ERM) binding phosphopro...
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Article
Solid-phase microextraction of 2,4,6-trinitrotoluene using a molecularly imprinted-based fiber
A molecularly imprinted polymer with trinitrotoluene as the template molecule was synthesized and used as the novel coating for solid-phase microextraction of the nitroaromatic explosive 2,4,6-trinitrotoluene ...
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Article
Improved silica xerogel film processing for MALDI-TOF–MS quantitative analysis of peptides and small molecules
In this work, sol–gel derived silica films were prepared for direct desorption/ionization of organic compounds in MALDI-TOF–MS analysis with the aim of improving method precision and of reducing interfering si...
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Article
Erratum to: Development of a combined SEM and ICP-MS approach for the qualitative and quantitative analyses of metal microparticles and sub-microparticles in food products
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Article
Development of a combined SEM and ICP-MS approach for the qualitative and quantitative analyses of metal microparticles and sub-microparticles in food products
An integrated approach based on the use of inductively coupled plasma mass spectrometry (ICP-MS) and scanning electron microscopy (SEM) for the qualitative and quantitative analyses of metal particles in foods...
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Article
Planar solid-phase microextraction-ion mobility spectrometry: a diethoxydiphenylsilane-based coating for the detection of explosives and explosive taggants
A novel diethoxydiphenylsilane-based coating for planar solid-phase microextraction was developed using sol–gel technology and used for ion mobility spectrometric detection of the explosives 2,4,6-trinitrotolu...
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Article
Open AccessAurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer
AZD1152, the prodrug for AZD1152-hydroxyquinazoline pyrazol anilide (HQPA), is a selective inhibitor of Aurora B kinase activity. Preclinical evaluation of AZD1152 has been reported in several human cancer mod...
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Article
Use of specific peptide biomarkers for quantitative confirmation of hidden allergenic peanut proteins Ara h 2 and Ara h 3/4 for food control by liquid chromatography–tandem mass spectrometry
A liquid chromatography–electrospray-tandem mass spectrometry (LC–ESI-MS–MS) method based on the detection of biomarker peptides from allergenic proteins was devised for confirming and quantifying peanut aller...
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Article
Liquid chromatography-electrospray ionization tandem mass spectrometry and liquid chromatography with fluorescence detection for determination of octylphenol and nonylphenol in municipal wastewater at trace levels
Reversed-phase liquid chromatography with fluorescence detection (RPLC-FD) and with electrospray ionization (ESI) tandem mass spectrometric detection (RPLC-ESI-MS-MS), both coupled with automated solid-phase s...
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Article
Failure of primary breast cancer neoangiogenesis to predict pattern of distant metastasis
In the present study, the primary tumor angiogenesis characteristics of 81 stage IV previously untreated breast cancers with synchronous metastasis to different distant sites (10 patients with soft tissue met...
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Article
Validation of a high-performance liquid chromatographic method for determination of isoflavonoids in soybeans. Study of the extraction procedure by experimental design
An improved analytical method, reversed-phase high-performance liquid chromatography on a narrow-bore C18 column, has been developed for the simultaneous determination of genistein, daidzein, formononetin, and bi...
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Article
Development of gas chromatographic method for determination of cholesterol oxides in meat products
A method of extraction, purification and gas chromatographic analysis of five cholesterol oxidation products (COPs) (7β-hydroxycholesterol, 5α, 6α-epoxycholesterol, 25-hydroxycholesterol, 7-ketocholesterol and...
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Article
Determination of phylloquinone (vitamin K1) by high performance liquid chromatography with UV detection and with particle beam-mass spectrometry
A reversed-phase PB LC-MS method was used for the determination and unequivocal identification of vitamin K1 in some vegetable samples. The method was also applied to the identification of other constituents in t...
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Article
Identification of vitamins A, D and E by particle beam liquid chromatography-mass spectrometry
Particle beam (PB) high performance liquid chromatography (HPLC)-mass spectrometry (MS) has been studied to investigate its suitability for the analysis of fat-soluble vitamins, as an example of thermally labi...
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Article
Randomised Clinical Trial of Adjuvant Chemotherapy in Patients with Node-Negative, Fast-Proliferating Breast Cancer
A prospective randomised clinical trial in patients with node-negative, fast-proliferating breast cancer was initiated in January 1990 to verify the feasibility and reliability of a 3H-thymidine (3H-Tdr) autoradi...
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Article
Thrombosis, recurrent abortions and intrauterine foetal death in a patient with lupus anticoagulant
The authors describe a case report of a patient suffering from thrombosis and recurrent abortions. Routine coagulation screening was abnormal and investigation showed the presence of a circulating anticoagulan...
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Article
Pentacoordination in dibromo-N-2-methylthiophenyl-2′-pyridylmethyleneiminezinc
The crystal structure of dibromo-N-2-methylthiophenyl-2′-pyridylmethyleneiminezinc has been determined and refined by Fourier and least-squares methods toR = 0·058 using three-dimensional X-ray data collected at ...
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Article
Crystal and molecular structure of di-μ-chloro(dicyandiamide)cadmium(II)
The crystal structure of di-μ-chloro(dicyandiamide)cadmium(II) has been determined and refined by Fourier and least-squares methods toR = 0·037 using three-dimensional X-ray data collected at room-temperature on ...
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Article
Crystal and molecular structure of tetrakis(N,N′-diallylthiourea)nickel(II) iodide
The crystal structure of tetrakis(N,N′-diallylthiourea)nickel(II) iodide [Ni(C7H12N2S)4I2] has been determined by a three-dimensional X-ray analysis. FinalR, after anisotropic least-squares refinement, is 8·8%. T...
