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Article
Crenobalneotherapy for low back pain: systematic review of clinical trials
Crenobalneotherapy is a treatment commonly used in Europe and Middle East. It uses mineral water sometimes combined with different hydrotherapy techniques. Most patients treated in spa centers suffer from low ...
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Chapter and Conference Paper
Studies on O2-TiO2 Interplay Toward Unconventional MOX-Based Optodes for Oxygen Detection
Titanium dioxide (TiO2) is a functional semiconductor metal oxide that plays a major role in the many applicative fields, mostly including water remediation, surface functionalization and photoanodes for photoele...
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Chapter and Conference Paper
UV-Cured Composite Films Containing ZnO Nanostructures: Effect of Filler Shape on Piezoelectric Response
In this work, a facile aqueous sol-gel approach was exploited for synthesizing different ZnO nanostructures; these latter were employed at 4 wt% loading in a UV-curable acrylic system. The piezoelectric behavi...
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Article
Hydroxychloroquine neuromyotoxicity: a case with rapid course and complete recovery
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Article
Comparative assessment of glucose prediction models for patients with type 1 diabetes mellitus applying sensors for glucose and physical activity monitoring
The present work presents the comparative assessment of four glucose prediction models for patients with type 1 diabetes mellitus (T1DM) using data from sensors monitoring blood glucose concentration. The four...
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Article
Erratum to: One-year follow-up of mud-bath therapy in patients with bilateral knee osteoarthritis: a randomized, single-blind controlled trial
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Article
One-year follow-up of mud-bath therapy in patients with bilateral knee osteoarthritis: a randomized, single-blind controlled trial
The objective of this prospective parallel randomized single-blind study was to assess that a cycle of mud-bath therapy (MBT) provides any benefits over usual treatment in patients with bilateral knee osteoart...
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Article
Induced psoriasis after rituximab therapy for rheumatoid arthritis: a case report and review of the literature
Rituximab is a human/murine monoclonal antibody targeting the CD20 antigen on B-lymphocytes surface. Although it has been licensed for treatment of non-Hodgkin’s lymphoma, nowadays it is also a novel therapy f...
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Article
Open AccessVEGF-A polymorphisms predict progression-free survival among advanced castration-resistant prostate cancer patients treated with metronomic cyclophosphamide
No data are available on the pharmacogenetics of metronomic chemotherapy in prostate cancer. The aim of this study was to evaluate the association between VEGF-A sequence variants and prostate-specific antigen (P...
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Article
Fasitibant prevents the bradykinin and interleukin 1β synergism on prostaglandin E2 release and cyclooxygenase 2 expression in human fibroblast-like synoviocytes
This study investigates the effect of the selective and potent B2 receptor antagonist fasitibant (MEN16132) on the proinflammatory effect of bradykinin (BK) and its interaction with interleukin 1β (IL-1β) in huma...
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Article
Open AccessSerum amyloid A circulating levels and disease activity in patients with juvenile idiopathic arthritis
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Article
Open AccessCirculating levels of the adipocytokines vaspin and omentin in patients with Kawasaki disease
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Article
Open AccessPharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer
The identification of molecular and genetic markers to predict or monitor the efficacy of bevacizumab (BV) represents a key issue in the treatment of metastatic colorectal cancer (mCRC).
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Article
Open AccessAurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer
AZD1152, the prodrug for AZD1152-hydroxyquinazoline pyrazol anilide (HQPA), is a selective inhibitor of Aurora B kinase activity. Preclinical evaluation of AZD1152 has been reported in several human cancer mod...
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Article
Open AccessAntiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib
Metronomic chemotherapy refers to the administration of chemotherapy at low, nontoxic doses on a frequent schedule with no prolonged breaks. The aim of the study is to rationally develop a CPT-11 metronomic re...
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Article
Open AccessA pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients
The pharmacokinetics (PK) and pharmacodynamics (PD) of metronomic irinotecan have not been studied in cancer patients. The aim of the study is to investigate the PK/PD profile of irinotecan/SN-38 administered ...
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Article
Open AccessFluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells
The new combination between the nucleoside analogue gemcitabine and the cholesterol-lowering drug fluvastatin was investigated in vitro and in vivo on the human pancreatic tumour cell line MIAPaCa-2. The present ...
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Article
Bobble-head doll syndrome due to a suprasellar arachnoid cyst: endoscopic treatment in two cases
We report two cases of bobble-head doll syndrome associated with a large suprasellar arachnoid cyst successfully treated with a minimally invasive endoscopic approach.
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Article
Structure and mechanical properties of low stress tetrahedral amorphous carbon films prepared by pulsed laser deposition
Tetrahedral amorphous carbon films have been produced by pulsed laser deposition, at a wavelength of 248 nm, ablating highly oriented pyrolytic graphite at room temperature, in a 10-2 Pa vacuum, at fluences rangi...
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Article
Capillaroscopic Findings in Erosive and Nodal Osteoarthritis of the Hands
Osteoarthritis of the hands is a very common disease that can present a large number of different clinic pictures, such as nodal (NOA) and erosive (EOA) forms. EOA in particular is a rare subset of hand osteo...