75 Result(s)
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**yong Peng
Biomedicine
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Article
Open AccessAdvances in spatial transcriptomics and its applications in cancer research
Malignant tumors have increasing morbidity and high mortality, and their occurrence and development is a complicate process. The development of sequencing technologies enabled us to gain a better understanding...
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An effective cross-scenario remote heart rate estimation network based on global–local information and video transformer
Remote photoplethysmography (rPPG) technology is a non-contact physiological signal measurement method, characterized by non-invasiveness and ease of use. It has broad application potential in medical health, ...
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Affective EEG-based cross-session person identification using hierarchical graph embedding
The electroencephalogram (EEG) signal is being investigated as a more confidential biometric for person identification. Despite recent advancements, a persistent challenge lies in the influence of variations i...
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Trends in statin use for the primary prevention of atherosclerotic cardiovascular disease among US adults by demographic characteristics, 1999–2020
Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of mortality worldwide. Statins, which are effective in preventing ASCVD, are underused, particularly for primary prevention. This study examin...
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Semi-supervised bipartite graph construction with active EEG sample selection for emotion recognition
Electroencephalogram (EEG) signals are derived from the central nervous system and inherently difficult to camouflage, leading to the recent popularity of EEG-based emotion recognition. However, due to the non...
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Article
In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies
Mice adoptively transferred with mouse B cells edited via CRISPR to express human antibody variable chains could help evaluate candidate vaccines and develop better antibody therapies. However, current editing...
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Transcription Factor TFAP2B Exerts Neuroprotective Effects Targeting BNIP3-Mediated Mitophagy in Ischemia/Reperfusion Injury
Cerebral ischemia–reperfusion injury (CIRI) leads to malignant brain edema, blood–brain barrier destruction, and neuronal apoptosis. N6-methyladenosine (m6A) RNA modification in CIRI was still limited explored...
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Open AccessAn angel or a devil? Current view on the role of CD8+ T cells in the pathogenesis of myasthenia gravis
Myasthenia gravis (MG) and the experimental autoimmune MG (EAMG) animal model are characterized by T-cell-induced and B-cell-dominated autoimmune diseases that affect the neuromuscular junction. Several subtyp...
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Galectin-3 Mediates Endotoxin Internalization and Caspase-4/11 Activation in Tubular Epithelials and Macrophages During Sepsis and Sepsis-Associated Acute Kidney Injury
Besides being recognized by membrane receptor TLR4, lipopolysaccharide (LPS) can also be internalized into the cytosol and activate Caspase-4/11 pyroptotic pathways to further amplify inflammation in sepsis. T...
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Open AccessBehavioral variant frontotemporal dementia associated with GRN and ErbB4 gene mutations: a case report and literature review
To report the clinical manifestation and genetic characteristics of a patient having frontotemporal dementia (FTD) with abnormal behavior and unstable walking.
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Open AccessCell-therapy for Parkinson’s disease: a systematic review and meta-analysis
Cell-based strategies focusing on replacement or protection of dopaminergic neurons have been considered as a potential approach to treat Parkinson’s disease (PD) for decades. However, despite promising precli...
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ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis
Reactive oxygen species (ROS) mediate lipid peroxidation and produce 4-hydroxynonenal and other related products, which play an important role in the process of cell death, including apoptosis, autophagy, and ...
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Article
MiR-29a-3p negatively regulates circulating Tfh memory cells in patients with Graves’ disease by targeting ICOS
MicroRNAs (miRNAs) are small endogenous noncoding RNAs that regulate genome expression posttranscriptionally and are involved in autoimmune diseases. Previous studies have indicated that follicular helper T (T...
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Article
A multi-omics integrative network map of maize
Networks are powerful tools to uncover functional roles of genes in phenotypic variation at a system-wide scale. Here, we constructed a maize network map that contains the genomic, transcriptomic, translatomic...
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Open AccessEvaluating the prognostic value of CD56 in pediatric acute myeloid leukemia
Many cytogenetic changes and gene mutations are associated with acute myeloid leukemia (AML) survival outcomes. CD56 is related to poor prognosis when expressed in adult AML patients. However, the prognostic v...
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Open AccessEffects of Malate Ringer's solution on myocardial injury in sepsis and enforcement effects of TPP@PAMAM-MR
Myocardial dysfunction played a vital role in organ damage after sepsis. Fluid resuscitation was the essential treatment in which Lactate Ringer's solution (LR) was commonly used. Since LR easily led to hyperl...
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Genome sequencing reveals evidence of adaptive variation in the genus Zea
Maize is a globally valuable commodity and one of the most extensively studied genetic model organisms. However, we know surprisingly little about the extent and potential utility of the genetic variation foun...
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Open AccessHistones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells
Neutrophil extracellular traps (NETs) can capture and kill viruses, such as influenza viruses, human immunodeficiency virus (HIV), and respiratory syncytial virus (RSV), thus contributing to host defense. Cont...
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Open AccessProteolysis-targeting chimeras (PROTACs) in cancer therapy
Proteolysis-targeting chimeras (PROTACs) are engineered techniques for targeted protein degradation. A bifunctional PROTAC molecule with two covalently-linked ligands recruits target protein and E3 ubiquitin l...
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Article
A novel classification method for EEG-based motor imagery with narrow band spatial filters and deep convolutional neural network
The Common Spatial Pattern (CSP) algorithm is the most widely used method for decoding Electroencephalography (EEG) signals from motor imagery (MI) paradigm. However, due to the inter-subject variability, the ...
