272 Result(s)
within
**yan Xu
English
Science, Humanities and Social Sciences, multidisciplinary
Science, multidisciplinary
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Article
Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms
Carbonic anhydrase, a zinc enzyme found in organisms from all kingdoms, catalyses the reversible hydration of carbon dioxide and is used for inorganic carbon acquisition by phytoplankton. In the oceans, where ...
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Article
Coexistence of Fermi arcs and Fermi pockets in a high-Tc copper oxide superconductor
One outstanding puzzle in high-temperature cuprate superconductors relates to the 'Fermi surface pocket' that is expected to emerge when the material is slightly doped or underdoped. Such pockets were recently...
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Article
Open AccessNanomechanical DNA origami 'single-molecule beacons' directly imaged by atomic force microscopy
DNA origami involves the folding of long single-stranded DNA into designed structures with the aid of short staple strands; such structures may enable the development of useful nanomechanical DNA devices. Here...
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Open AccessStructure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine
ELIC, the pentameric ligand-gated ion channel from Erwinia chrysanthemi, is a prototype for Cys-loop receptors. Here we show that acetylcholine is a competitive antagonist for ELIC. We determine the acetylcholine...
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Electronic origin of high-temperature superconductivity in single-layer FeSe superconductor
The recent discovery of high-temperature superconductivity in iron-based compounds has attracted much attention. How to further increase the superconducting transition temperature (Tc) and how to understand the s...
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Open AccessTunable Dirac Fermion Dynamics in Topological Insulators
Three-dimensional topological insulators are characterized by insulating bulk state and metallic surface state involving relativistic Dirac fermions which are responsible for exotic quantum phenomena and poten...
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Open AccessSuper-paramagnetic responsive nanofibrous scaffolds under static magnetic field enhance osteogenesis for bone repair in vivo
A novel nanofibrous composite scaffold composed of super-paramagnetic γ-Fe2O3 nanoparticles (MNP), hydroxyapatite nanoparticles (nHA) and poly lactide acid (PLA) was prepared using electrospinning technique. The ...
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Disappearance of nodal gap across the insulator–superconductor transition in a copper-oxide superconductor
The parent compound of the copper-oxide high-temperature superconductors is a Mott insulator. Superconductivity is realized by do** an appropriate amount of charge carriers. How a Mott insulator transforms i...
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Orbital-selective spin texture and its manipulation in a topological insulator
Topological insulators represent a new quantum state of matter that are insulating in the bulk but metallic on the edge or surface. In the Dirac surface state, it is well-established that the electron spin is ...
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Article
Identification of genomic alterations in oesophageal squamous cell cancer
Using whole-genome and whole-exome sequencing, this study identifies eight significantly mutated genes in oesophageal squamous cell cancer, including two genes, ADAM29 and FAM135B, not previously associated with ...
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Article
Open AccessStrong Anisotropy of Dirac Cones in SrMnBi2 and CaMnBi2 Revealed by Angle-Resolved Photoemission Spectroscopy
The Dirac materials, such as graphene and three-dimensional topological insulators, have attracted much attention because they exhibit novel quantum phenomena with their low energy electrons governed by the re...
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Article
Open AccessNetwork based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma
LCN2 (lipocalin 2) is a member of the lipocalin family of proteins that transport small, hydrophobic ligands. LCN2 is elevated in various cancers including esophageal squamous cell carcinoma (ESCC). In this study...
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Open AccessIdentification of a novel salt tolerance gene in wild soybean by whole-genome sequencing
Using a whole-genome-sequencing approach to explore germplasm resources can serve as an important strategy for crop improvement, especially in investigating wild accessions that may contain useful genetic reso...
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Article
Open AccessEvidence of Topological Surface State in Three-Dimensional Dirac Semimetal Cd3As2
The three-dimensional topological semimetals represent a new quantum state of matter. Distinct from the surface state in the topological insulators that exhibits linear dispersion in two-dimensional momentum p...
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Dichotomy of the electronic structure and superconductivity between single-layer and double-layer FeSe/SrTiO3 films
The latest discovery of possible high-temperature superconductivity in the single-layer FeSe film grown on a SrTiO3 substrate has generated much attention. Initial work found that, while the single-layer FeSe/SrT...
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Article
Open AccessA designed peptide targeting CXCR4 displays anti-acute myelocytic leukemia activity in vitro and in vivo
Leukemia cells highly expressing chemokine receptor CXCR4 can actively response to stroma derived factor 1α (CXCL12), trafficking and homing to the marrow microenvironment, which causes poor prognosis and rela...
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Article
Structures of bacterial homologues of SWEET transporters in two distinct conformations
The X-ray crystal structures of two bacterial homologues of the SWEET sugar transporters are solved in two conformational states, and comparison of these states suggests that transport occurs via a ‘rocker-swi...
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Article
Open AccessPhotodiode-Like Behavior and Excellent Photoresponse of Vertical Si/Monolayer MoS2 Heterostructures
Monolayer transition metal dichalcogenides (TMDs) and their van der Waals heterostructures have been experimentally and theoretically demonstrated as potential candidates for photovoltaic and optoelectronic de...
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Article
Open AccesssiRNA induces gelsolin gene transcription activation in human esophageal cancer cell
Recent studies show that targeting gene promoter or 3′ terminal regions of mRNA with siRNA induces target gene transcription. However, the ability of exon-targeting siRNA to affect transcription has yet to be ...
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Open AccessMiRNA-320 in the human follicular fluid is associated with embryo quality in vivo and affects mouse embryonic development in vitro
Previous work from our laboratory demonstrated the existence of miRNAs in human follicular fluid. In the current study, we have sought to identify miRNAs that might affect oocyte/embryo quality in patients und...
