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Article
Open AccessLoss of multipotency in adipose-derived stem cells after culture in temperature-responsive injectable polymer hydrogels
Adipose-derived stem cells (AdSCs), a type of mesenchymal stem cell, are expected to be applicable to regenerative medicine and cellular delivery systems. The maintenance of cell multipotency and control of th...
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Chapter
Correction to: Molecular Material for Molecular Robots
Correction to: Chapter 6 in: S. Murata (ed.), Molecular Robotics, https://doi.org/10.1007/978-981-19-3987-7_6
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Chapter
Molecular Material for Molecular Robots
Various molecular devices and materials that may extend the functionality of molecular robots and broaden the field of application such as DNA hydrogels utilizing G-quadruplexes, DNA hydrogels with branched DN...
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Article
Special issue: Biofunctional gels
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Article
Open AccessControl of swarming of molecular robots
Recently we demonstrated swarming of a self-propelled biomolecular motor system microtubule (MT)-kinesin where interactions among thousands of motile MTs were regulated in a highly programmable fashion by usin...
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Article
Open AccessDNA-assisted swarm control in a biomolecular motor system
In nature, swarming behavior has evolved repeatedly among motile organisms because it confers a variety of beneficial emergent properties. These include improved information gathering, protection from predator...
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Article
Analysis of the sol-to-gel transition behavior of temperature-responsive injectable polymer systems by fluorescence resonance energy transfer
Amphiphilic triblock copolymers of poly(ethylene glycol) (PEG) and aliphatic polyesters such as poly(ɛ-caprolactone-co-glycolide) (PCGA) are typical examples of thermogelling polymers. In the gelation mechanis...
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Article
Open AccessA DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly
DNA aptamers have potential for disease diagnosis and as therapeutics, particularly when interfaced with programmable molecular technology. Here we have combined DNA aptamers specific for the malaria biomarker Pl...
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Article
Automatic Recognition of DNA Pliers in Atomic Force Microscopy Images
Bottom-up fabrication techniques are expected to alleviate the limitations of top-down fabrication. Bottom-up fabrication requires self-assembling facilities to construct complex structures including DNA nanos...
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Article
Encapsulation of a gold nanoparticle in a DNA origami container
A ‘box-shaped’ three-dimensional (3D) DNA origami of ~40-nm dimensions was selectively formed by closing a symmetric open motif with three orthogonal faces. This 3D DNA origami was used as an intelligent nano-...
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Article
Instant preparation of a biodegradable injectable polymer formulation exhibiting a temperature-responsive sol–gel transition
We developed a very quick and convenient preparative method for an injectable polymer (IP) formulation to overcome solubility problems of IPs. We investigated the effects of various additives on the dispersion...
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Article
DNA nanostructures as scaffolds for metal nanoparticles
The rapid development of DNA nanotechnology has enabled the precise bottom-up integration of metal nanoparticles (NPs) on a nanometer scale. The recent introduction of the DNA origami technique has facilitated...
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Article
Open AccessNanomechanical DNA origami 'single-molecule beacons' directly imaged by atomic force microscopy
DNA origami involves the folding of long single-stranded DNA into designed structures with the aid of short staple strands; such structures may enable the development of useful nanomechanical DNA devices. Here...
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Article
Simultaneous genoty** of indels and SNPs by mass spectroscopy
Nucleotide insertion/deletion polymorphisms (indels) in ApoE gene were precisely genotyped using artificial ribonucleases and MALDI-TOF MS. The RNA fragments for MS analysis were prepared by treating RNA specimen...
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Article
Cooperation of metal-ion fixation and target-site activation for efficient site-selective RNA scission
Iminodiacetate–DNA conjugates and acridine–DNA conjugates were synthesized and combined for site-selective RNA hydrolysis by Lu(III). When these conjugates form a ternary complex with complementary RNA, the Lu...
