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Article
Alcohol drinking and colorectal cancer: A population-based prospective cohort study in China
Study objective: To asses the association between alcohol consumption and the risk of colorectal cancer (CRC) in the Chinese population. Design: A population-based prospective cohort study was initiated ...
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Article
Baculovirus per os infectivity factors are involved in HearNPV ODVs infection of HzAM1 cells in vitro
Baculoviruses produce two viral phenotypes, the budded virus (BV) and the occlusion-derived virus (ODV). ODVs are released from occlusion bodies in the midgut where they initiate a primary infection. Due to th...
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Article
Side effects during treatment of advanced gastric carcinoma by chemotherapy combined with CIK-cell transfusion in elderly people
To study the side effects and therapeutic results of autologous cytokine-induced killer (CIK) cell treatment in elderly patients with advanced gastric cancer.
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Article
Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma
B7-H3, a member of the B7-family molecules, plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 was expresse...
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Article
Tumor expression of B7-H4 predicts poor survival of patients suffering from gastric cancer
To establish the prognostic value of B7-H4 expression by tumor cells in gastric cancer patients, we evaluated the association of B7-H4 expression with clinicopathologic factors and overall survival of gastric ...
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Article
B7-H4 expression and increased death risk of cancer patients: A meta-analysis
The relationship between higher levels of B7-H4 expression and death risk of cancer patients remains to be clarified. In the current study, information from an ordinary scale and those from several outcome sca...
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Article
Review of Chinese clinical trials on CIK cell treatment for malignancies
China is the country where the most clinical trials on CIK cells have been performed. We aimed to provide definite evidence for using CIK cell treatment and extrapolate a common applicative standard for malign...
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Article
Open AccessComputed tomography-guided permanent brachytherapy for locoregional recurrent gastric cancer
Locoregional recurrence is the typical pattern of recurrence in gastric cancer, and cannot be removed by surgery in most of the patients. We aimed to evaluate the feasibility and efficacy of computed tomograph...
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Article
miR-17-5p Inhibitor Enhances Chemosensitivity to Gemcitabine Via Upregulating Bim Expression in Pancreatic Cancer Cells
miR-17-5p is reported to be overexpressed in pancreatic cancer, and it plays an important role in carcinogenesis and cancer progression. Gemcitabine is the standard first-line chemotherapeutic agent for pancre...
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Article
Open AccessEfficacy of adjuvant immunotherapy with cytokine-induced killer cells in patients with locally advanced gastric cancer
To determine the long-term efficacy of adjuvant immunotherapy with autologous cytokine-induced killer (CIK) cells for locally advanced gastric cancer patients.
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Article
Higher numbers of T-bet+ intratumoral lymphoid cells correlate with better survival in gastric cancer
In the present study, we studied the expression of T-bet, a key marker for type 1 immune responses, within the tumor microenvironment of gastric cancer, and analyzed its association with clinicopathological pa...
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Article
Serum lemur tyrosine kinase 3 expression in colorectal cancer patients predicts cancer progression and prognosis
Lemur tyrosine kinase-3 (LMTK3) is a member of the families of serine–threonine–tyrosine kinases, which has been suggested to be a possible target and marker of breast cancer. However, its definitive physiopathol...
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Open AccessRETRACTED ARTICLE: Up-regulated miR-199a-5p in gastric cancer functions as an oncogene and targets klotho
Recent studies have shown that miR-199a-5p plays opposite roles in cancer initiation and progression of different cancer types, acting as oncogene for some cancer types but as tumor suppressor gene for others....
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Article
Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process anomalies in individual breast cancers
The goal of this analysis was to develop a computational tool that integrates the totality of gene expression, DNA copy number, and sequence abnormalities in individual cancers in the framework of biological p...
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Article
The relationships between the chemosensitivity of human gastric cancer to paclitaxel and the expressions of class III β-tubulin, MAPT, and survivin
Lack of effective biomarkers is one of the challenges in current chemotherapy to predict drug response and sensitivity. This study was carried out to investigate the relationships between the expressions of cl...
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Article
Expression of costimulatory molecules B7-H1, B7-H4 and Foxp3+ Tregs in gastric cancer and its clinical significance
Immune escape plays an important role in tumor progression. In the present study, the expression of B7-H1, B7-H4 and Foxp3 involved in immune escape in gastric carcinoma was investigated and the corresponding ...
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Article
hcrcn81 promotes cell proliferation through Wnt signaling pathway in colorectal cancer
The objective of the study was to investigate the role of hcrcn81 gene in Wnt/β-catenin signaling pathway related to human colorectal cancer. A total of 30 pairs of human colorectal cancer tissues with contro...
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Article
Open AccessLack of association between bovine leukemia virus and breast cancer in Chinese patients
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Open AccessA prediction model for lymph node metastases using pathologic features in patients intraoperatively diagnosed as stage I non-small cell lung cancer
There is little information on which pattern should be chosen to perform lymph node dissection for stage I non-small-cell lung cancer. This study aimed to develop a model for predicting lymph node metastasis u...
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Article
Interleukin-33 Expression does not Correlate with Survival of Gastric Cancer Patients
The aim of the study was to investigate IL-33 expression in gastric cancer (GC) and its association with the clinical characteristics and the prognosis. IL-33 protein in tumor and corresponding adjacent tissue...