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  1. No Access

    Article

    Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process anomalies in individual breast cancers

    The goal of this analysis was to develop a computational tool that integrates the totality of gene expression, DNA copy number, and sequence abnormalities in individual cancers in the framework of biological p...

    Weiwei Shi, Balint Balazs, Balazs Györffy… in Breast Cancer Research and Treatment (2014)

  2. Article

    Open Access

    New network topology approaches reveal differential correlation patterns in breast cancer

    Analysis of genome-wide data is often carried out using standard methods such as differential expression analysis, clustering analysis and heatmaps. Beyond that, differential correlation analysis was suggested...

    Michael Bockmayr, Frederick Klauschen, Balazs Györffy… in BMC Systems Biology (2013)

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  3. Article

    Open Access

    Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue – a GC-TOFMS based metabolomics study

    Changes in energy metabolism of the cells are common to many kinds of tumors and are considered a hallmark of cancer. Gas chromatography followed by time-of-flight mass spectrometry (GC-TOFMS) is a well-suited...

    Jan Budczies, Carsten Denkert, Berit M Müller, Scarlet F Brockmöller… in BMC Genomics (2012)

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  4. No Access

    Article

    An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

    Validating prognostic or predictive candidate genes in appropriately powered breast cancer cohorts are of utmost interest. Our aim was to develop an online tool to draw survival plots, which can be used to ass...

    Balazs Györffy, Andras Lanczky, Aron C. Eklund… in Breast Cancer Research and Treatment (2010)

  5. No Access

    Article

    Meta-analysis of gene expression profiles related to relapse-free survival in 1,079 breast cancer patients

    The transcriptome of breast cancers have been extensively screened with microarrays and large sets of genes associated with clinical features have been established. The aim of this study was to validate origin...

    Balazs Györffy, Reinhold Schäfer in Breast Cancer Research and Treatment (2009)

  6. No Access

    Article

    Highly expressed genes are associated with inverse antisense transcription in mouse

    There is a growing evidence, that antisense transcription might have a key role in a range of human diseases. Although predefined sense-antisense pairs were extensively studied, the antisense expression of the...

    Andras Györffy, Pawel Surowiak, Zsolt Tulassay, Balazs Györffy in Journal of Genetics (2007)