15 Result(s)

Article

Emerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways

The interaction between programmed cell death ligand 1 (PD-L1), which is expressed on the surface of tumor cells, and programmed cell death 1 (PD-1), which is expressed on T cells, impedes the effective activa...

Rong Wang, Shiwei He, Jun Long, Yian Wang… in Experimental Hematology & Oncology (2024)

Article

The mechanism of action and experimental verification of Gan-song Yin on renal clear cell carcinoma based on network pharmacology and bioinformatics

Gan-song Yin (GSY) is originated from the scripture “Gan-song Pills”, a medical work of the Ningxia ethnic minorities, and its treatment of kidney diseases has good results. Its method of treating Renal clear ...

Wenjie Jiang, Ling Yuan, Qian Liu, **angyang Li, Yifan Yang… in Discover Oncology (2024)

Article

The roles and molecular mechanisms of non-coding RNA in cancer metabolic reprogramming

One of the key features of cancer is energy metabolic reprogramming which is tightly related to cancer proliferation, invasion, metastasis, and chemotherapy resistance. NcRNAs are a class of RNAs having no pro...

Shizhen Li, Ming**g Peng, Shiming Tan, Linda Oyang… in Cancer Cell International (2024)

Article

Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

As a subclass of endogenous stable noncoding RNAs, circular RNAs are beginning to be appreciated for their potential as tumor therapeutics. However, the functions and mechanisms by which circRNAs exert protect...

Deze Zhao, Ye** Dong, Minghao Duan, Dan He… in Journal of Experimental & Clinical Cancer … (2023)

Article

Proteomic profiling of gastric cancer with peritoneal metastasis identifies a protein signature associated with immune microenvironment and patient outcome

Peritoneal metastasis (PM) frequently occurs in patients with gastric cancer (GC) and is a major cause of mortality. Risk stratification for PM can optimize decision making in GC treatment.

Yanyan Chen, Guoxin Cai, Junjie Jiang, Chao He, Yiran Chen, Yongfeng Ding… in Gastric Cancer (2023)

Article

Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment

Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet their growth requirements. Metab...

Shiming Tan, Yiqing Yang, Wenjuan Yang… in Journal of Experimental & Clinical Cancer … (2023)

Article

The function of prohibitins in mitochondria and the clinical potentials

Prohibitins (PHBs) are a class of highly evolutionarily conserved proteins that widely distribute in prokaryotes and eukaryotes. PHBs function in cell growth and proliferation or differentiation, regulating me...

Linda Oyang, Jian Li, **anjie Jiang, **guan Lin… in Cancer Cell International (2022)

Article

Comment on: “Phase II study of S-1 and oxaliplatin as neoadjuvant chemotherapy for locally advanced adenocarcinoma of the gastric or esophagogastric junction: KSCC1601. Gastric cancer, 2021 Aug 11” by Iwatsuki et al

Yongfeng Ding, Junjie Jiang, Nong Xu in Gastric Cancer (2021)

Article

Letter to the editor: new response evaluation criteria using early morphological change in imatinib treatment for patients with gastrointestinal stromal tumor

Junjie Jiang, Lisong Teng in Gastric Cancer (2021)

Article

Comment on: “Association between triglyceride-glucose index and gastric carcinogenesis: a health checkup cohort study. Gastric cancer, 2021 Aug 5” by Kim et al.

Junjie Jiang, Lisong Teng in Gastric Cancer (2021)

Article

A novel genomic classification system of gastric cancer via integrating multidimensional genomic characteristics

Gastric cancer (GC) is one of the leading causes of cancer deaths with high heterogeneity. There is currently a paucity of clinically applicable molecular classification system to guide precise medicine.

Haiyong Wang, Yongfeng Ding, Yanyan Chen, Junjie Jiang, Yiran Chen… in Gastric Cancer (2021)

Article

Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2

Circular RNAs (circRNAs) are widely expressed in human cells and are closely associated with cancer development. However, they have rarely been investigated in the context of nasopharyngeal carcinoma (NPC).

Yongzhen Mo, Yumin Wang, Shuai Zhang, Fang **ong, Qijia Yan… in Molecular Cancer (2021)

Article

Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments

Vasculogenic mimicry (VM) is a recently discovered angiogenetic process found in many malignant tumors, and is different from the traditional angiogenetic process involving vascular endothelium. It involves th...

**aoxu Wei, Yunhua Chen, **anjie Jiang, Miao Peng, Yiduo Liu… in Molecular Cancer (2021)

Article

The role of microenvironment in tumor angiogenesis

Tumor angiogenesis is necessary for the continued survival and development of tumor cells, and plays an important role in their growth, invasion, and metastasis. The tumor microenvironment—composed of tumor ce...

**anjie Jiang, Jie Wang, **angying Deng… in Journal of Experimental & Clinical Cancer … (2020)

Article

Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape

Tumor immune escape is an important strategy of tumor survival. There are many mechanisms of tumor immune escape, including immunosuppression, which has become a research hotspot in recent years. The programme...

**anjie Jiang, Jie Wang, **angying Deng, Fang **ong, Junshang Ge… in Molecular Cancer (2019)