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  1. No Access

    Article

    Pharmacokinetics of nirmatrelvir/ritonavir and the drug-drug interaction with calcineurin inhibitor in renal transplant recipients

    To describe the pharmacokinetic (PK) characteristics of nirmatrelvir/ritonavir in renal transplant recipients and explore the potential factors that related to the PK variance of nirmatrelvir/ritonavir and its...

    Xueyin Xu, Huanxi Zhang, Longshan Liu, Qian Fu in European Journal of Clinical Pharmacology (2024)

  2. Article

    Open Access

    A review on the thermochemical reaction mechanisms for distiller pyrolysis process

    Circular utilization of distillery byproducts is crucial, and pyrolysis has emerged as a viable technology for converting them into fuels and high-value chemicals. This review investigates the thermochemical r...

    Sheng-Lun Lin, Hongjie Zhang, Wei-Hsin Chen, Yee-Lin Wu in Sustainable Environment Research (2024)

  3. No Access

    Article

    Evaluation of fragility fracture risk using deep learning based on ultrasound radio frequency signal

    It was essential to identify individuals at high risk of fragility fracture and prevented them due to the significant morbidity, mortality, and economic burden associated with fragility fracture. The quantitat...

    Wenqiang Luo, Jionglin Wu, Zhiwei Chen, Peidong Guo, Qi Zhang, Baiying Lei in Endocrine (2024)

  4. Article

    Open Access

    TaqTth-hpRNA: a novel compact RNA-targeting tool for specific silencing of pathogenic mRNA

    Pathogenic allele silencing is a promising treatment for genetic hereditary diseases. Here, we develop an RNA-cleaving tool, TaqTth-hpRNA, consisting of a small, chimeric TaqTth, and a hairpin RNA guiding prob...

    Chong Xu, Jiyanuo Cao, Huanran Qiang, Yu Liu, Jialin Wu, Qiudan Luo in Genome Biology (2024)

  5. Article

    Open Access

    Humid heat environment causes anxiety-like disorder via impairing gut microbiota and bile acid metabolism in mice

    Climate and environmental changes threaten human mental health, but the impacts of specific environmental conditions on neuropsychiatric disorders remain largely unclear. Here, we show the impact of a humid he...

    Huandi Weng, Li Deng, Tianyuan Wang, Huachong Xu, Jialin Wu in Nature Communications (2024)

  6. No Access

    Article

    Remediation of phenanthrene contaminated soil by persulphate coupled with Pseudomonas aeruginosa GZ7 based on oxidation prediction model

    Chemical oxidation coupled with microbial remediation has attracted widespread attention for the removal of polycyclic aromatic hydrocarbons (PAHs). Among them, the precise evaluation of the feasible oxidant c...

    Zhenxian Yao, **angyuan Zhou, Tao ** in Environmental Science and Pollution Resear… (2024)

  7. No Access

    Article

    The Effect of Sintering Temperature on the Microstructure and Electrical Properties of ZnO–Bi2O3 Varistor Ceramics

    The effect of sintering temperature on the microstructure and electrical properties of ZnO–Bi2O3 varistor ceramics was studied in the present work. Results demonstrate that the Bi-rich phase ZnBi38O60 is generate...

    **g**g Tian, Yelin Wu, Heng Tian, Yonghao Xu in Journal of Electronic Materials (2024)

  8. No Access

    Article

    Cytokines-activated nuclear IKKα-FAT10 pathway induces breast cancer tamoxifen-resistance

    Endocrine therapy that blocks estrogen signaling is the most effective treatment for patients with estrogen receptor positive (ER+) breast cancer. However, the efficacy of agents such as tamoxifen (Tam) is often ...

    Xueyan Chen, Weilin Wu, Ji-Hak Jeong, Matjaz Rokavec in Science China Life Sciences (2024)

  9. Article

    Open Access

    Analysis of tumor microenvironment alterations in partially responsive rectal cancer patients treated with neoadjuvant chemoradiotherapy

    Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy ...

    Hong Chen, Ji-Hong Zhang, Qin Hao in International Journal of Colorectal Disease (2024)

  10. Article

    Open Access

    The effect of biochar on crop productivity and soil salinity and its dependence on experimental conditions in salt-affected soils: a meta-analysis

    Biochar can significantly alter soil properties and therefore can play an important role in increasing the resilience of agricultural systems to salt conditions. To match biochar to salt-affected soil constrai...

    Baolin Wu, Heng Yang, Siyuan Li, Jun Tao in Carbon Research (2024)

  11. No Access

    Article

    Comparing Mechanical and Oxidation Properties of Cr- and Si-Alloyed Press-Hardened Steel with 22MnB5 Steel at Various Heating Temperatures

    High-performance press-hardened steels (PHS) are highly desired in automotive body-in-white due to their excellent strength and crashworthiness. PHS alloyed with high Cr and Si show promise in enhancing oxidat...

    Zhuo Cheng, **yue Liu, Huiwen Yu in Metallurgical and Materials Transactions A (2024)

  12. Article

    Open Access

    Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy

    Recently, environmental temperature has been shown to regulate bone homeostasis. However, the mechanisms by which cold exposure affects bone mass remain unclear. In our present study, we observed that exposure...

    Li-Min Lei, Fu-**ng-Zi Li, **ao Lin, Feng Xu, Su-Kang Shan in Journal of Nanobiotechnology (2024)

  13. No Access

    Article

    Update on lacrimal apparatus dysfunction associated with differentiated thyroid cancer after I-131 therapy

    The most prevalent lacrimal apparatus dysfunctions associated with differentiated thyroid cancer(DTC) after I-131 therapy are dry eye and nasolacrimal duct obstruction(NLDO), leading to ocular discomfort and l...

    Chunlan Liang, Changlin Wu, Lian Liu, **gxiang Zhong in International Ophthalmology (2024)

  14. No Access

    Article

    Marine aquaculture can deliver 40% lower carbon footprints than freshwater aquaculture based on feed, energy and biogeochemical cycles

    Freshwater aquaculture is an increasingly important source of blue foods but produces substantial methane and nitrous oxide emissions. Marine aquaculture, also known as mariculture, is a smaller sector with a ...

    Lu Shen, Lidong Wu, Wei Wei, Yi Yang, Michael J. MacLeod, **tai Lin in Nature Food (2024)

  15. No Access

    Article

    Utilization of novel bubbling device for continuous measurement of radon in water

    Radon can move freely through air and water. Water radon measurement is a method of earthquake monitoring and water radon can be used as an environmental tracer to follow transit pathways. A novel bubbling dev...

    Tao Hu, Zhongkai Fan, Shuaibin Liu in Journal of Radioanalytical and Nuclear Che… (2024)

  16. Article

    Open Access

    CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity

    The interaction between glioblastoma cells and glioblastoma-associated macrophages (GAMs) influences the immunosuppressive tumor microenvironment, leading to ineffective immunotherapies. We hypothesized that d...

    Chan-Chuan Liu, Wen-Bin Yang, Chia-Hung Chien, Cheng-Lin Wu in Cell Death & Disease (2024)

  17. No Access

    Article

    Microwave excited hyperthermy and catalysis of heterostructured Au/Cu–BTA for effective bacteria killing by accelerating charge separation

    Deep tissue infections caused by pathogenic bacteria seriously threat the lives of patients. In this study, a smart heterostructured Au/Cu–BTA (BTA = 1,2,4,5-benzenetetramine) with microwave (MW) response is s...

    Wen-**g Zhang, Li-Guo **, Shui-Lin Wu, Chao-Feng Wang, Yu-Feng Zheng in Rare Metals (2024)

  18. No Access

    Article

    Gender and Age Differences in the Evaluation and Clinical Outcomes of Patients with Palpitations

    Palpitations represent a common clinic complaint.

    Sun Young Jeong MD, MPH, Aiyu Chen MPH in Journal of General Internal Medicine (2024)

  19. Article

    Open Access

    Microgels for Cell Delivery in Tissue Engineering and Regenerative Medicine

  20. This review provides a comprehensive summary associated with recent progress in the preparation and application of microgels.

  21. ...
  22. Leyan Xuan, Yingying Hou, Lu Liang, Jialin Wu, Kai Fan, Liming Lian in Nano-Micro Letters (2024)

  23. Article

    Open Access

    Resilient, environment tolerant and biocompatible electroluminescent devices with enhanced luminance based on compliant and self-adhesive electrodes

    Electroluminescent (EL) devices are of great significance for expanding the application range of optoelectronics. However, the realization of EL devices with environment-tolerance, stretchability, mechanical c...

    Ya Lu, Yuanyuan Chen, Haoyu Sun, Fang Deng, Changtong Mei in npj Flexible Electronics (2024)

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