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Article
Pharmacokinetics of nirmatrelvir/ritonavir and the drug-drug interaction with calcineurin inhibitor in renal transplant recipients
To describe the pharmacokinetic (PK) characteristics of nirmatrelvir/ritonavir in renal transplant recipients and explore the potential factors that related to the PK variance of nirmatrelvir/ritonavir and its...
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Article
RENAL nephrometry scoring system in bilateral Wilms tumor: predictive application
This study aims to explore the application of RENAL nephrometry scoring system in bilateral Wilms tumor (BWT).
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Article
Open AccessGenotype and phenotype analysis and transplantation strategy in children with kidney failure caused by NPHP
Nephronophthisis-related ciliopathies (NPHP-RC) have strong genotype and phenotype heterogeneity, and the transplantation strategy of Boichis syndrome is still controversial. Our purpose was to examine associa...
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Article
Open AccessMicroRNA profile of circulating CD4+ T cells in aged patients with atherosclerosis obliterans
To evaluate the specificity of the expression patterns of microRNAs (miRNAs) in circulating CD4+ T cells in aged patients with atherosclerosis obliterans (ASO).
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Ischemia and Reperfusion Injury in Organ Transplantation from Cardiac Death Donors
The maintenance of normal functions of tissues and organs depends on good blood circulation. When the blood supply stops or drops, the nutrition and oxygen supply of the tissue cannot meet the needs, resulting...
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Article
Open AccessClinical analysis of 13 children with primary hyperoxaluria type 1
A retrospective statistical analysis of primary hyperoxaluria type 1 (PH1) in children from June 2016 to May 2019 was carried out to discover its clinical and molecular biological characteristics. Patients wer...
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Article
Open AccessAn accessible insight into genetic findings for transplantation recipients with suspected genetic kidney disease
Determining the etiology of end-stage renal disease (ESRD) constitutes a great challenge in the context of renal transplantation. Evidence is lacking on the genetic findings for adult renal transplant recipien...
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Article
Pediatric kidney transplantation in China: an analysis from the IPNA Global Kidney Replacement Therapy Registry
The International Pediatric Nephrology Association (IPNA) Global Kidney Replacement Therapy (KRT) Registry was established to evaluate the incidence and outcomes of kidney replacement therapy (dialysis and tra...
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Article
Open AccessCOVID-19-related medical research: a meta-research and critical appraisal
Since the start of the COVID-19 outbreak, a large number of COVID-19-related papers have been published. However, concerns about the risk of expedited science have been raised. We aimed at reviewing and catego...
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Article
Open AccessTransplantation of a single kidney from pediatric donors less than 10 kg to children with poor access to transplantation: a two-year outcome analysis
Access to kidney transplantation by uremic children is very limited due to the lack of donors in many countries. We sought to explore small pediatric kidney donors as a strategy to provide transplant opportuni...
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Article
Prediction of mizoribine pharmacokinetic parameters by serum creatinine in renal transplant recipients
Mizoribine (MZR) is an immunosuppressive agent with extensive inter-individual differences in pharmacokinetics (PK). Here, we investigated the PK characteristics of MZR in renal transplant recipients and gave ...
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Article
Open AccessDown-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer
OPCML belongs to the IgLON family of Ig domain–containing GPI-anchored cell adhesion molecules and was recently found to be involved in carcinogenesis, while its role in gastric cancer remains unclear.
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Article
Open AccessGinkgo biloba extract EGb761 attenuates brain death-induced renal injury by inhibiting pro-inflammatory cytokines and the SAPK and JAK-STAT signalings
This study aimed to investigate the protective effects of EGb761, a Ginkgo Biloba extract, against brain death-induced kidney injury. Sixty male Sprague Dawley rats were randomly divided into six groups: sham, br...
