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  1. Article

    Open Access

    Mitochondrial DNA Copy Number as a Biomarker for Guiding Adjuvant Chemotherapy in Stages II and III Colorectal Cancer Patients with Mismatch Repair Deficiency: Seeking Benefits and Avoiding Harms

    Colorectal cancer (CRC) patients with mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) status are conventionally perceived as unresponsive to adjuvant chemotherapy (ACT). The mitochondria...

    Mian Chen PhD, Shenghe Deng MD, Yinghao Cao MD, Jun Wang PhD in Annals of Surgical Oncology (2024)

  2. No Access

    Article

    Factors related to accurate clinicians’ prediction of survival: an international multicenter study in East Asia

    Recent guidelines for prognostic evaluation recommend clinicians’ prediction of survival (CPS) for survival prediction in patients with advanced cancer. However, CPS is often inaccurate and optimistic. Studies...

    Yusuke Hiratsuka, Sang-Yeon Suh, Seok Joon Yoon, Sung-Eun Choi in Supportive Care in Cancer (2024)

  3. Article

    Open Access

    Study Protocol: Global Research Initiative on the Neurophysiology of Schizophrenia (GRINS) project

    Objective and quantifiable markers are crucial for develo** novel therapeutics for mental disorders by 1) stratifying clinically similar patients with different underlying neurobiological deficits and 2) obj...

    Jun Wang, Chenguang Jiang, Zhenglin Guo, Sinéad Chapman in BMC Psychiatry (2024)

  4. Article

    Open Access

    Relationship between jejunum ATPase activity and antioxidant function on the growth performance, feed conversion efficiency, and jejunum microbiota in Hu sheep (Ovis aries)

    ATPase activity and the antioxidant function of intestinal tissue can reflect intestinal cell metabolic activity and oxidative damage, which might be related to intestinal function. However, the specific influ...

    Zhanyu Chen, Guoxiu Wang, Weimin Wang, **aojuan Wang in BMC Veterinary Research (2024)

  5. Article

    Open Access

    Molecular subtypes of breast cancer identified by dynamically enhanced MRI radiomics: the delayed phase cannot be ignored

    To compare the diagnostic performance of intratumoral and peritumoral features from different contrast phases of breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) by building radiomics mode...

    Guoliang Huang, Siyao Du, Si Gao, Liangcun Guo, Ruimeng Zhao in Insights into Imaging (2024)

  6. Article

    Open Access

    Prevalence of unhealthy behaviors and their associations with non-suicidal self-injury, suicidal ideation and suicide attempt among Chinese adolescents

    Unhealthy lifestyle behaviors among adolescents have emerged as a significant public health concern worldwide, however, there is little investigation on the impact of unhealthy behaviors on non-suicidal self-i...

    Wenjian Lai, Herui Wu, Liwen Yang in Child and Adolescent Psychiatry and Mental… (2024)

  7. Article

    Open Access

    Associations between immune cell phenotypes and lung cancer subtypes: insights from mendelian randomization analysis

    Lung cancer is a common malignant tumor, and different types of immune cells may have different effects on the occurrence and development of lung cancer subtypes, including lung squamous cell carcinoma (LUSC) ...

    **-Min Zheng, Chen-** Lou, Yu-Liang Huang, Wen-Tao Song in BMC Pulmonary Medicine (2024)

  8. No Access

    Article

    Cox model risk score to predict survival of intrahepatic cholangiocarcinoma after ultrasound-guided ablation

    To explore factors associated with overall survival (OS) and progression-free survival (PFS) of intrahepatic cholangiocarcinoma (iCCA) after ultrasound-guided ablation and establish a model for survival risk e...

    Yueting Sun, Baoxian Liu, Hui Shen, Yi Zhang, Ruiying Zheng in Abdominal Radiology (2024)

  9. No Access

    Article

    EBV-associated lymphoproliferative disease post-CAR-T cell therapy

    Epstein–Barr virus (EBV)-associated lymphoproliferative diseases (EBV-LPDs) are common complications that occur after solid organ transplantation or allogeneic hematopoietic stem-cell transplantation (HSCT). H...

    Shiyuan Zhang, **aoxi Zhou, Shangkun Zhang, Na Wang, Tongcun Zhang in Frontiers of Medicine (2024)

  10. No Access

    Article

    Impact of endoscopic surveillance on the early diagnosis and endoscopic resection likelihood of gastric cancer

    Endoscopy could help detect early gastric cancer (EGC) and improve the prognosis of patients. The aim of this study was to analyze the impact of endoscopy and endoscopic surveillance on the early detection of ...

    Lu Sun, Yanjie Shen, Liang Huang, **g Zhao, Meng Li, Yue Hu, Bin Lyu in Surgical Endoscopy (2024)

  11. No Access

    Article

    An inferior vena cava-priority approach in laparoscopic isolated hepatic caudate lobectomy

    Laparoscopic isolated caudate lobectomy is still a challenging operation for surgeons. The access route of the operation plays a vital role during laparoscopic caudate lobectomy. There are few references regar...

    Lei Guo, **ao-Ying Zhu, Jie Xue, Ju-**an Sun in Langenbeck's Archives of Surgery (2024)

  12. Article

    Open Access

    Hepatitis B virus reactivation associated with CAR T-cell therapy

    Patients with hematological malignancies who also have a hepatitis B virus (HBV) infection need to be aware of the potential risk of HBV reactivation when undergoing anti-cancer treatments. Among these treatme...

    Haolong Lin, Zigang Dai, Liang Huang, **aoxi Zhou in Holistic Integrative Oncology (2024)

  13. No Access

    Article

    The prognostic value of vessels encapsulating tumor clusters (VETC) in patients with hepatocellular carcinoma: a systematic review and meta-analysis

    Studies have suggested that vessels encapsulating tumor clusters (VETC) is a strong predictor of prognosis in patients with hepatocellular carcinoma (HCC).

    Miaomiao Wang, Liang Cao, Yinzhong Wang in Clinical and Translational Oncology (2024)

  14. Article

    Open Access

    Correction: Assessing the impact of public funding in alleviating participant reduction and improving the retention rate in methadone maintenance treatment clinics in Taiwan: an interrupted time series analysis

    Yu-Chu Ella Chung, Yu-Chi Tung, Sheng-Chang Wang in Implementation Science (2024)

  15. No Access

    Article

    Construction and validation of the nomogram predictive model for post-percutaneous nephrolithotomy urinary sepsis

    This study aimed to construct and validate a simple and accurate clinical nomogram for predicting the occurrence of post-percutaneous nephrolithotomy sepsis, aiming to assist urologists in the early identifica...

    Zuze Qiu, Shun Zhan, Yuanming Song, Liang Huang, **g **e in World Journal of Urology (2024)

  16. No Access

    Article

    CircRUNX1 drives the malignant phenotypes of lung adenocarcinoma through mediating the miR-5195-3p/HMGB3 network

    Circular RNAs (circRNAs) are key factors in the regulation of cancer progression. However, the role of circRUNX1 in lung adenocarcinoma (LUAD) progression is unclear.

    Yan Wang, Hui Li, Wenbin Chen in General Thoracic and Cardiovascular Surgery (2024)

  17. Article

    Open Access

    Effects of uric acid-lowering therapy (ULT) on renal outcomes in CKD patients with asymptomatic hyperuricemia: a systematic review and meta-analysis

    It is well known that asymptomatic hyperuricemia and gout play an important role in patients with chronic kidney disease (CKD). However, the effect of uric acid-lowering therapy (ULT) on the prognosis of CKD p...

    Yuxin Luo, Qirong Song, Jiaxiao Li, Sha Fu, Wenjuan Yu, **aofei Shao in BMC Nephrology (2024)

  18. Article

    Open Access

    Assessing the impact of public funding in alleviating participant reduction and improving the retention rate in methadone maintenance treatment clinics in Taiwan: an interrupted time series analysis

    Given the steady decline in patient numbers at methadone maintenance treatment (MMT) clinics in Taiwan since 2013, the government initiated Patients’ Medical Expenditure Supplements (PMES) in January 2019 and...

    Yu-Chu Ella Chung, Yu-Chi Tung, Sheng-Chang Wang in Implementation Science (2024)

  19. No Access

    Article

    3D fusion is superior to 2D point-to-point contrast-enhanced US to evaluate the ablative margin after RFA for hepatocellular carcinoma

    To compare the efficiency of three-dimensional (3D) and two-dimensional (2D) contrast-enhanced ultrasound (CEUS)–derived techniques in evaluating the ablative margin (AM) after radiofrequency ablation (RFA) fo...

    Haiyi Long, **aoyu Zhou, **aoer Zhang, Jieyi Ye, Tongyi Huang in European Radiology (2024)

  20. Article

    Open Access

    Interpretable artificial intelligence-based app assists inexperienced radiologists in diagnosing biliary atresia from sonographic gallbladder images

    A previously trained deep learning-based smartphone app provides an artificial intelligence solution to help diagnose biliary atresia from sonographic gallbladder images, but it might be impractical to launch ...

    Wenying Zhou, Zejun Ye, Guangliang Huang, **aoer Zhang, Ming Xu in BMC Medicine (2024)

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