13,184 Result(s)

Article

Correction: MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma

Qin Tang, Wan Li, **ang** Zheng, Liwen Ren… in Signal Transduction and Targeted Therapy (2024)

Article

Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study

This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion radiotherapy (CIRT) alone or as a boost strategy after photon radiatio...

**aoJun Li, YanShan Zhang, YanCheng Ye, SuQing Tian, TingChao Hu, HongYu Chai… in BMC Cancer (2024)

Article

Pegylated recombinant human granulocyte colony-stimulating factor for primary prophylaxis of neutropenia in patients with cervical cancer receiving concurrent chemoradiotherapy: a prospective study

This study aimed to investigate the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) for primary prophylaxis of neutropenia in patients with cervical cance...

**g You, Yidi Yuan, **aoxuan Gu, Weihu Wang, **aofan Li in BMC Cancer (2024)

Article

Nomogram for predicting the probability of rectal anastomotic re-leakage after stoma closure: a retrospective study

In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after stoma closure.

Yuegang Li, Gang Hu, **zhu Zhang, Wenlong Qiu, Shiwen Mei, **shan Wang… in BMC Cancer (2024)

Article

An analysis of the role of GAB2 in pan-cancer from a multidimensional perspective

To explore the role of GAB2 in pan-cancer based on bioinformatics analysis.

Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang… in Discover Oncology (2024)

Article

Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases

Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether pyroptosis can be a death form of MC remains unknown. Proteasom...

Zhan-Li Chen, Chen **e, Wei Zeng, Rui-Qi Huang… in Signal Transduction and Targeted Therapy (2024)

Article

eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma

Extracellular heat shock protein 90 AA1(eHSP90α) is intricately linked to tumor progression and prognosis. This study aimed to investigate the difference in the value of eHSP90α in post-treatment response asse...

Yingzhen Bian, Haizhou Liu, **glei Huang, Zhaorong Feng, Yanyan Lin… in BMC Cancer (2024)

Article

Correction: A CT based radiomics analysis to predict the CN0 status of thyroid papillary carcinoma: a two- center study

Zongbao Li, Yifan Zhong, Yan Lv, Jianzhong Zheng, Yu Hu, Yanyan Yang… in Cancer Imaging (2024)

Article

Correction: Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy

Yu-An Li, Chuan Zhao, **g-**g Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi… in BMC Cancer (2024)

Article

N⁶-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor

The potential involvement of circular RNAs (circRNAs) and N⁶-methyladenosine (m⁶A) modification in the progression of Wilms tumor (WT) has not been fully elucidated. This study investigates the regulatory mechani...

Guannan Shu, Zhang Zhao, Tianxin Zhao… in Journal of Experimental & Clinical Cancer … (2024)

Article

Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study

Most gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has significantly improved the survival of patients with GISTs. We aimed to evalu...

Hui-Jen Tsai, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai… in BMC Cancer (2024)

Article

A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression

The aberrant expression of phosphofructokinase-platelet (PFKP) plays a crucial role in the development of various human cancers by modifying diverse biological functions. However, the precise molecular mechani...

Weiwei Liu, Zhao Ding, Ye Tao, Shixian Liu, Maoyu Jiang, Fangzheng Yi… in Molecular Cancer (2024)

Article

Synthetic CT generation for pelvic cases based on deep learning in multi-center datasets

To investigate the feasibility of synthesizing computed tomography (CT) images from magnetic resonance (MR) images in multi-center datasets using generative adversarial networks (GANs) for rectal cancer MR-onl...

**anan Li, Lecheng Jia, Fengyu Lin, Fan Chai, Tao Liu, Wei Zhang… in Radiation Oncology (2024)

Article

Develo** a deep learning model for predicting ovarian cancer in Ovarian-Adnexal Reporting and Data System Ultrasound (O-RADS US) Category 4 lesions: A multicenter study

To develop a deep learning (DL) model for differentiating between benign and malignant ovarian tumors of Ovarian-Adnexal Reporting and Data System Ultrasound (O-RADS US) Category 4 lesions, and validate its di...

Wenting **e, Wenjie Lin, ** Li… in Journal of Cancer Research and Clinical On… (2024)

Article

Novel associations between MTDH gene polymorphisms and invasive ductal breast cancer: a case–control study

To reveal the contributing effects of MTDH gene SNPs in the risk of invasive ductal breast cancer (IDC).

Yan Huang, Dan Dai, Li Zhu, **anzhong Qi in Discover Oncology (2024)

Article

Surgical outcomes of major vascular resection for retroperitoneal liposarcoma from a high‑volume sarcoma center: a propensity score matching analysis

Radical resection of retroperitoneal liposarcoma (RLPS) may necessitate vascular resection and reconstruction. The study was conducted to assess surgical outcomes of surgery for RLPS with major vascular involv...

Guoqiang Xue, **aopeng Wang, Bonan Liu… in Journal of Cancer Research and Clinical On… (2024)

Article

ZBTB7A regulates LncRNA HOTAIR-mediated ELAVL1/SOX17 axis to inhibit malignancy and angiogenesis in endometrial carcinoma

Endometrial cancer (EC) is the sixth most frequent cancer in women worldwide and has higher fatality rates. The pathophysiology of EC is complex, and there are currently no reliable methods for diagnosing and ...

**ao-Hui Zhang, Shu-Wei Wu, Yi-Fan Feng… in Journal of Cancer Research and Clinical On… (2024)

Article

Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression

Cholangiocarcinoma (CCA), characterized by high heterogeneity and extreme malignancy, has a poor prognosis. Doublecortin-like kinase 1 (DCLK1) promotes a variety of malignant cancers in their progression. Targ...

Ziwei Liang, Yang Ge, Jianjian Li… in Journal of Cancer Research and Clinical On… (2024)

Article

Association of body composition indicators with colorectal cancer: a hospital-based case-control study

Colorectal cancer (CRC) is a common malignancy that affects adults worldwide, causing a high disease burden. Few studies have examined the relationship between body composition (BC) measures and the prevalence...

Qiu** Chen, Kai Li, Yang Liu, **aozhai Yu… in Journal of Cancer Research and Clinical On… (2024)

Article

Investigation of prognostic values of immune infiltration and LGMN expression in the microenvironment of osteosarcoma

Osteosarcoma (OS), the most common primary malignant bone tumor, predominantly affects children and young adults and is characterized by high invasiveness and poor prognosis. Despite therapeutic advancements, ...

Hualiang Xu, Dawei Xu, Yinfeng Zheng, Huajun Wang, Aiguo Li… in Discover Oncology (2024)